Marom Bikson, PhD
Education
Research Fellow, Neurophysiology Unit, University of Birmingham Medical School, U.K., 2003
Ph.D., Biomedical Engineering, Case Western Reserve University Cleveland, OH, 2000
B.S., Biomedical Engineering (EE Concentration), Johns Hopkins University, Baltimore, MD, 1995
Research Areas and Expertise
Prof. Marom Bikson’s research group studies the effects of electricity on the human body and applies this knowledge toward the development of medical devices and electrical safety guidelines.
“Our goal is to improve human health by combining engineering innovation, with cutting-edge experimental techniques, and original bio-medical insight. This challenge requires creative problem-solving, precision, and imagination. We are tremendously fortunate to access the extensive resources of the City University of New York research centers and of the New York Center for Biomedical Engineering hospital network.”
Specific areas of research include:
Medical devices including biosensors, drug delivery technology, and electrotherapy devices for neurological disorders.
Medical device safety including electrical hazards, electroporation, heating damage, and safe stimulation protocols.
Electrical safety, electric shock hazards, and accidental electrocution.
Understanding the neuronal networks underlying normal brain function, including the role of endogenous electric fields.
Developing new treatments for neurological diseases including epilepsy and depression, through translational research.
Prof. Bikson’s group uses a range of research and engineering design tools including cellular and animal studies, computer simulations, imaging, and clinical evaluation. Prof. Bikson’s research has received support from funding agencies including NIH (NINDS,NCI,NIGMS, NIMH), DoD (AFRL), The Andy Grove Foundation, The Wallace H. Coulter Foundation, The Epilepsy Foundation, and the Howard Hughes Medical Institute. Prof. Bikson is co-founder of Soterix Medical Inc. and Safe Toddles.
Prof. Bikson is actively involved in biomedical education including outreach to underserved groups. Prof. Bikson is founding chairman of Neuromodec and its events including the NYC-Neuromodulation conference and the Neuromodec tDCS Workshop.
Prof. Bikson has provided extensive technical support and consulting for biomedical companies (GSK, Boston Scientific, NuSkin…), utility companies (Con Edison, First Energy), government agencies (NIH, DoD, NASA, NY State Public Service Commission…), and litigation support.
View Prof. Bikson’s CV: VIEW
Prof. Bikson is co-director of Neural Engineering at The City College of New York and the New York Center for Biomedical Engineering. More project information at CCNY Neural Engineering.
Selected Publications
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2024
Tarek K Rajji, Christopher R Bowie, Nathan Herrmann, Bruce G Pollock, Krista L Lanctôt, Sanjeev Kumar, Alastair J Flint, Linda Mah, Corinne E Fischer, Meryl A Butters, Marom Bikson, James L Kennedy, Daniel M Blumberger, Zafiris J Daskalakis, Damien Gallagher, Mark J Rapoport, Nicolaas P L G Paul Verhoeff , Angela C Golas, Ariel Graff-Guerrero, Erica Vieira, Aristotle N Voineskos, Heather Brooks, Ashley Melichercik, Kevin E Thorpe, Benoit H Mulsant; PACt-MD Study Group. Slowing Cognitive Decline in Major Depressive Disorder and Mild Cognitive Impairment: A Randomized Clinical Trial. JAMA Psychiatry. 2024 Oct 30:e243241. doi: 10.1001/jamapsychiatry.2024.3241.
N. Gebodh. M, Bikson Response regarding: Frontal HD-tACS enhances behavioral and EEG biomarkers of vigilance in continuous attention task (2024) Brain Stimulation. DOI: 10.1016/j.brs.2024.11.004
N. Khadka, Z. Deng, S. Lisanby, M. Bikson, J. Camprodon. Computational Models of High-Definition Electroconvulsive Therapy for Focal or Multitargeting Treatment. The Journal of ECT ():10.1097/YCT.0000000000001069, August 26, 2024. | DOI: 10.1097/YCT.0000000000001069
J.S Ho, C. Poon, R. North, W. Grubb, S. Lempka, M. Bikson, (2024) A Visual and Narrative Timeline Review of Spinal Cord Stimulation Technology and US Food and Drug Administration Milestones. Neuromodulation: Technology at the Neural Interface 27,: 6 https://doi.org/10.1016/j.neurom.2024.05.006 PDF
B. Wang, A.V. Peterchev, G. Gaugain, R.J. Ilmoniemi, W.M. Grill, M. Bikson, D. Nikolayev. (2024) Quasistatic approximation in neuromodulation. Journal of Neural Engineering. Jul 24;21(4). doi: 10.1088/1741-2552/ad625e. PDF
M. Muccio, G. Pilloni, L.W. Masters, P. He, L. Krupp, A. Datta, M. Bikson, L. Charvet, Y. Ge (2024) Simultaneous and cumulative effects of tDCS on cerebral metabolic rate of oxygen in multiple sclerosis. Front. Hum. Neurosci. 18:1418647. doi: 10.3389/fnhum.2024.1418647 PDF
N. Gebodh, V. Miskovic, S. Laszlo, A. Datta, M. Bikson (2024) Frontal HD-tACS Enhances Behavioral and EEG Biomarkers of Vigilance in Continuous Attention Task. Brain Stimulation journal, DOI:https://doi.org/10.1016/j.brs.2024.05.009
F. Farahani, N. Khadka, L.C. Parra, M. Bikson, M. Vöröslakos. (2024) Transcranial electric stimulation modulates firing rate at clinically relevant intensities. Brain Stimulation. https://doi.org/10.1016/j.brs.2024.04.007 PDF
E. Silva-Filho, M. Bikson, N. Gebodh, N. Khadka, A. Santos, R. Pegado, M. Brasileiro-Santos. (2024) A pilot randomized controlled trial of transcranial direct current stimulation adjunct to moderate-intensity aerobic exercise in hypertensive individuals. Frontiers in Neuroergonomics. https://doi.org/10.3389/fnrgo.2024.1236486
M. Bikson, M. Sharma (2024). A Brief History of Slow Spinal Potentials, Gate Theory of Pain, and Spinal Cord Stimulation. Neuromodulation Technology at the Neural Interface DOI:https://doi.org/10.1016/j.neurom.2023.12.001 PDF
A.F.L. Cavalcante, J.S.C. Brito Holanda, J.O.S. Passos, J.M.P. de Oliveira, E. Morya, A.H. Okano, M. Bikson, R. Pegado. (2024). Anodal tDCS over the motor cortex improves pain but not physical function in chronic chikungunya arthritis: Randomized controlled trial, Annals of Physical and Rehabilitation Medicine. 67:4 https://doi.org/10.1016/j.rehab.2024.101826. PDF
2023
G. Soleimani, J. Joutsa, K. Moussawi, S.H. Siddiqi, R. Kuplicki, M. Bikson, M.P. Paulus, M.D. Fox, C.A. Hanlon, H. Ekhtiari. (2023) Converging Evidence for Frontopolar Cortex as a Target for Neuromodulation in Addiction Treatment. American Journal of Psychiatry. https://doi.org/10.1176/appi.ajp.20221022
J Douglas Bremner; Asim H Gazi; Tamara P Lambert; Afra Nawar; Anna B Harrison; Justine W Welsh; Viola Vaccarino; Kevin M Walton; Nora Jaquemet; Kellen Mermin-Bunnell; Hewitt Mesfin; Trinity A Gray; Keyatta Ross; Georgia Saks; Nikolina Tomic; Danner Affadzi; Marom Bikson; Amit J Shah; Kelly E Dunn; Nicholas A Giordano; Omer T Inan. (2023) Ann Depress Anxiety. 10(1): 1117. PDF
Giuseppina Pilloni, Hyein Cho, Tian Esme Tian, Joerg Beringer, Marom Bikson, Leigh Charvet. (2023) . Immediate and Differential Response to Emotional Stimuli Associated With Transcranial Direct Current Stimulation for Depression: A Visual-Search Task Pilot Study. Neuromodulation. https://doi.org/10.1016/j.neurom.2023.07.006 in press
Carine El Jamal, Ashley Harrie, Annalise Rahman-Filipiak, Alexandru D Iordan, Alexandre F DaSilva, Robert Ploutz-Snyder, Lara Khadr, Michael Vesia, Marom Bikson, Benjamin M Hampstead. (2023) Tolerability and blinding of high-definition transcranial direct current stimulation among older adults at intensities of up to 4 mA per electrode. Brain Stimulation https://doi.org/10.1016/j.brs.2023.08.025 in press
Soleimani, G., Nitsche, M. A., Bergmann, T. O., Towhidkhah, F., Violante, I. R., Lorenz, R., Kuplicki, R., Tsuchiyagaito, A., Mulyana, B., Mayeli, A., Ghobadi-Azbari, P., Mosayebi-Samani, M., Zilverstand, A., Paulus, M. P., Bikson, M., & Ekhtiari, H. (2023). Closing the loop between brain and electrical stimulation: towards precision neuromodulation treatments. Translational Psychiatry, 13, 279(2023). https://doi.org/10.1038/s41398-023-02565-5 PDF
Khadka, N., Poon, C., Cancel, L. M., Tarbell, J. M., & Bikson, M. (2023). Multi-scale multi-physics model of brain interstitial water flux by transcranial Direct Current Stimulation. Journal of Neural Engineering, 20(4), 046014. https://doi.org/10.1088/1741-2552/ace4f4 PDF
Sabé, M., Sulstarova, A., Chen, C., Hyde, J., Poulet, E., Aleman, A., Downar, J., Brandt, V., Mallet, L., Sentissi, O., Nitsche, M. A., Bikson, M., Brunoni, A. R., Cortese, S., & Solmi, M. (2023). A century of research on neuromodulation interventions: A scientometric analysis of trends and knowledge maps. Neuroscience & Biobehavioral Reviews, 152(2023), 105300. https://doi.org/10.1016/j.neubiorev.2023.105300 PDF
Bahr-Hosseini, M., Nael, K., Unal, G., Iacoboni, M., Liebeskind, D. S., Bikson, M., & Saver, J. L. (2023). High-definition Cathodal Direct Current Stimulation for Treatment of Acute Ischemic Stroke: A Randomized Clinical Trial. JAMA Network Open, 6(6), 2319231. doi:10.1001/jamanetworkopen.2023.19231 PDF
Bikson, M., & Giordano, J. (2023). Defining distinction between real vs hypothetical problems in the ethics of neurotechnology. Brain Stimulation, 16(3), 977-979. https://doi.org/10.1016/j.brs.2023.05.016 PDF
Sharma, M., Bhaskar, V., Yang, L., FallahRad, M., Gebodh, N., Zhang, T., Esteller, R., Martin, J., & Bikson, M. (2023). Novel Evoked Synaptic Activity Potentials (ESAPs) Elicited by Spinal Cord Stimulation. eNeuro, 10(5) https://doi.org/10.1523/ENEURO.0429-22.2023 PDF
Pilloni, G., Masters, L. W., Muccio, M., Choi, C., Datta, A., Bikson, M., Krupp, L., Ge, Y., & Charvet, L. (2023). Is Fatigue Response to tDCS Mediated by Change in Affect? An Open-label tDCS-MRI Study (S27. 010). Neurology, 100(17.S2). https://doi.org/10.1212/WNL.0000000000202970
Bikson, M., Ganho-Ávila, A., Datta, A., Gillick, B., Joensson, M. G., Kim, S., Kim, J., Kirton, A., Lee, K., Marjenin, T., Onarheim, B., Rehn, E. M., Sack, A. T., & Unal, G. (2023). Limited output transcranial electrical stimulation 2023 (LOTES-2023): Updates on engineering principles, regulatory statutes, and industry standards for wellness, over-the-counter, or prescription devices with low risk. Brain Stimulation, 16(3), 840-853. https://doi.org/10.1016/j.brs.2023.05.008 PDF
Rajagopalan, N. R., Vista, WR., Fujimori, M., Vroomen, L. G.P.H., Jimenéz, J. M., Khadka, N., Bikson, M., & Srimathveeravalli, G. (2023). Cytoskeletal Remodeling and Gap Junction Translocation Mediates Blood–Brain Barrier Disruption by Non-invasive Low-Voltage Pulsed Electric Fields. Annals of Biomedical Engineering (2023), 1-14. https://doi.org/10.1007/s10439-023-03211-3 PDF
Unal, G., Poon, C., FallahRad, M., Thahsin, M., Argyelan, M., & Bikson, M. (2023). Quasi-static pipeline in electroconvulsive therapy computational modeling. Brain Stimulation, 16(2), 607-618. https://doi.org/10.1016/j.brs.2023.03.007 PDF (cover)
Bikson, M. (2023). Transcranial direct current stimulation and neurovascular modulation. European Journal of Neurology, 30(4), 802-803. https://doi.org/10.1111/ene.15710 PDF (commentary)
Bahr-Hosseini, M., Nael, K., Iacoboni, M., Liebeskind, D. S., Bikson, M., & Saver, J. L. (2023). Abstract WP36: Transcranial Electrical Stimulation (tdcs) In Stroke Early After Onset Clinical Trial (tesseract). Stroke, 54(Suppl_1), AWP36-AWP36. https://doi.org/10.1161/str.54.suppl_1.WP36
Santana, K., França, E., Sato, J., Silva, A., Queiroz, M., Farias J., Rodrigues, D., Souza, I., Ribeiro, V., Caparelli-Dáquer, E., Teixeira, A. L., Charvet, L., Datta, A., Bikson, M., & Andrade, S. (2023). Non-invasive brain stimulation for fatigue in post-acute sequelae of SARS-CoV-2 (PASC). Brain Stimulation, 16(1), 100-107. https://doi.org/10.1016/j.brs.2023.01.1672 PDF
Gaugain, G., Quéguiner, L., Bikson, M., Sauleau, R., Zhadobov, M., Modolo, J., & Nikolayev, D. (2023). Quasi-static approximation error of electric field analysis for transcranial current stimulation. Journal of Neural Engineering, 20(1). https://doi.org/10.1088/1741-2552/acb14d PDF
Unal, G., Poon, C., FallahRad, M., Thahsin, M., Argyelan, M., & Bikson, M. (2023). Quasi-static assumption in electroconvulsive therapy computational modeling. Brain Stimulation, 16(1), 402. https://doi.org/10.1016/j.brs.2023.01.816 PDF
Vogel-Eyny, A., Cho, H., Pilloni, G., George, A., Lustberg, M., Datta, A., Bikson, M., Nazim, K., Charlson, R. E., & Charvet, L. (2023). At-home telehealth transcranial direct current stimulation for treatment resistant depression. Brain Stimulation, 16(1), 344. https://doi.org/10.1016/j.brs.2023.01.658 PDF
Androulakis, M., Mangold, K., Harrison, A., Moore, R. D., Guo, S., Zhang, J., Datta, A., Bikson, M., & Charvet, L. (2023). Remotely Supervised tDCS for Persistent Post-Traumatic Headache in Veterans (ReStore). Brain Stimulation, 16(1), 278. https://doi.org/10.1016/j.brs.2023.01.477 PDF
Bahr-Hosseini, M., Nael, K., Iacoboni, M., Liebeskind, D., Bikson, M., & Saver, J. (2023). Transcranial Electrical Stimulation in Stroke EaRly After onset Clinical Trial (TESSERACT). Brain Stimulation, 16(1), 236. https://doi.org/10.1016/j.brs.2023.01.358 PDF
Pilloni, G., Charvet, L., Datta, A., & Bikson, M. (2023). Potential application of Transcranial Electrical Stimulation (tES) techniques in the context of COVID-19 clinical course: From theory to real-world application. Brain Stimulation, 16(1), 192. https://doi.org/10.1016/j.brs.2023.01.231 PDF
Andrade, S., França, E., Sato, J., Costa, L., Bezerra, M. E., Caparelli-Dáquer, E., Datta, A., & Bikson, M. (2023). Modulation of brain-lung interactions using HD-tDCS: Mechanisms, clinical practice, and recent advances. Brain Stimulation, 16(1), 114. https://doi.org/10.1016/j.brs.2023.01.1666 PDF
Bikson, M. (2023). Neuro-vascular modulation and brain response to transcranial electrical stimulation. Brain Stimulation, 16(1), 196. https://doi.org/10.1016/j.brs.2023.01.244 PDF
Charvet, L., Pilloni, G., George, A., Eilam-Stock, T., Lustberg, M., Datta, A., & Bikson, M. (2023). tDCS as telehealth intervention to reach patients with Post-Acute Sequelae of SARS-CoV-2 (PASC). Brain Stimulation, 16(1), 192-193. https://doi.org/10.1016/j.brs.2023.01.233 PDF
Andrade, S., França, E., Silvestre, C., Santana, K., Cintra, V., Sato, J., Caparelli-Dáquer, E., Hampstead, B., Teixeira, A., & Bikson, M. (2023). HD-tDCS in acute and long-term COVID-19. Brain Stimulation, 16(1), 191-192. https://doi.org/10.1016/j.brs.2023.01.230 PDF
Gebodh, N., Miskovic, V., Laszlo, S., Datta, A., & Bikson, M. (2023). A Scalable Framework for Closed-Loop Neuromodulation with Deep Learning. bioRxiv. https://doi.org/10.1101/2023.01.18.524615 PDF
2022
Cancel, L. M., Silas, D., Bikson, M., & Tarbell, J. M. (2022). Direct current stimulation modulates gene expression in isolated astrocytes with implications for glia-mediated plasticity. Scientific Reports, 12(17964). https://doi.org/10.1038/s41598-022-22394-8 PDF
Cavendish, B. A., Lima, A., Bertola, L., Charvet, L., Bikson, M., Brunoni, A. R., & Vidal, K. S. (2022). Combination of transcranial direct current stimulation with online cognitive training improves symptoms of Post-acute Sequelae of COVID-19: A case series. Brain Stimulation: Basic, Translational, and Clinical Research in Neuromodulation, 15(6), 1375-1377. https://doi.org/10.1016/j.brs.2022.09.008 PDF
Stefano, L. H., Favoretto, D. B., Nascimento, D. C., Santos, L. R. A., Bikson, M., Leite, J. P., Pontes-Neto, O. M., Edwards, D. J., & Edwards, T. G. S. (2022). Dataset of middle cerebral artery blood flow stability in response to high-definition transcranial electrical stimulation. Data in Brief, 45, 108603. https://doi.org/10.1016/j.dib.2022.108603 PDF
Muccio, M., Walton Masters, L., Pilloni, G., He, P., Krupp, L., Datta, A., Bikson, M., Charvet, L., & Ge, Y. (2022). Cerebral metabolic rate of oxygen (CMRO2) changes measured with simultaneous tDCS-MRI in healthy adults. Brain Research, 1796, 148097. https://doi.org/10.1016/j.brainres.2022.148097 PDF
Brunoni, A. R., Ekhtiari, H., Antal, A., Auvichayapat, P., Baeken, C., Benseñor, I. M., Bikson, M., Boggio, P., Borroni, B., Brighina, F., Brunelin, J., Carvalho, S., Caumo, W., Ciechanski, P., Charvet, L., Clark, V. P., Cohen Kadosh, R., Cotelli, M., Datta, A., Deng, ZD., De Raedt, R., De Ridder, D., Fitzgerald, P. B., Floel, A., Frohlich, F., George, M. S., Ghobadi-Azbari, P., Goerigk, S., Hamilton, R. H., Jaberzadeh, S. J., Hoy, K., Kidgell, D. J., Zanoozi, A. K., Kirton, A., Laureys, S., Lavidor, M., Lee, K., Leite, J., Lisanby, S. H., Loo, C., Martin, D. M., Miniussi, C., Mondino, M., Monte-Silva, K., Morales-Quezada, L., Nitsche, M. A., Okano, A. H., Oliveira, C. S., Onarheim, B., Pacheco-Barrios, K., Padberg, F., Nakamura-Palacios, E. M., Palm, U., Paulus, W., Plewnia, C., Priori, A., Rajji, T. K., Razza, L. B., Rehn, E. M., Ruffini, G., Schellhorn, K., Zare-Bidoky, M., Simis, M., Skorupinski, P., Suen, P., Thibaut, A., Valiengo, L. C.L., Vanderhasselt, MA., Vanneste, S., Venkatasubramanian, G., Violante, I. R., Wexler, A., Woods, A. J., & Fregni, F. (2022). Digitalized transcranial electrical stimulation: A consensus statement. Clinical Neurophysiology, 143, 154-165. https://doi.org/10.1016/j.clinph.2022.08.018 PDF
Schertz, M., Karni-Visel, Y., Genizi, J., Manishevitch, H., Lam, M., Akawi, A., Dudai, M., Fenton, A., & Bikson, M. (2022). Transcranial Direct Current Stimulation (tDCS) in children with ADHD: A randomized, sham-controlled pilot study. Journal of Psychiatric Research, 155, 302-312. https://doi.org/10.1016/j.jpsychires.2022.08.022 PDF
Zannou, A. L., Khadka, N., & Bikson, M. (2022). Bioheat Model of Spinal Column Heating During High-Density Spinal Cord Stimulation. Neuromodulation: Technology at the Neural Interface. https://doi.org/10.1016/j.neurom.2022.07.006 PDF
Badran, B. W., Huffman, S. M., Dancy, M., Austelle, C. W., Bikson, M., Kautz, S. A., & George, M. S. (2022). A pilot randomized controlled trial of supervised, at-home, self-administered transcutaneous auricular vagus nerve stimulation (taVNS) to manage long COVID symptoms. Bioelectronic Medicine, 8(13). https://doi.org/10.1186/s42234-022-00094-y PDF
Czura, C. J., Bikson, M., Charvet, L., Chen, J. D. Z., Franke, M., Fudim, M., Grigsby, E., Hamner, S., Huston, J. M., Khodaparast, N., Krames, E., Simon, B. J., Staats, P., & Vonck, K. (2022). Neuromodulation Strategies to Reduce Inflammation and Improve Lung Complications in COVID-19 Patients. Frontiers in Neurology, 13. https://doi.org/10.3389/fneur.2022.897124 PDF
Moreira, A., Moscaleski, L., Machado, D. G. da S., Bikson, M., Unal, G., Bradley, P. S., Cevada, T., da Silva, F. T. G., Baptista, A. F., Morya, E., & Okano, A. H. (2022). Transcranial direct current stimulation during a prolonged cognitive task: The effect on cognitive and shooting performances in professional female basketball players. Ergonomics, 66(4), 492-505. https://doi.org/10.1080/00140139.2022.2096262
Cardoso, L., Khadka, N., Dmochowski, J. P., Meneses, E., Lee, K., Kim, S., Jin, Y., & Bikson, M. (2022). Computational modeling of posteroanterior lumbar traction by an automated massage bed: Predicting intervertebral disc stresses and deformation. Frontiers in Rehabilitation Sciences, 3. https://doi.org/10.3389/fresc.2022.931274 PDF
Dmochowski, J.P., Khadka, N., Cardoso, L., Meneses, E., Lee, K., Kim, S., Jin, Y., & Bikson, M. (2022). Computational Modeling of Deep Tissue Heating by an Automatic Thermal Massage Bed: Predicting the Effects on Circulation. Frontiers in Medical Technology, 4. https://doi.org/10.3389/fmedt.2022.925554 PDF
Pilloni, G., Charvet, L. E., Bikson, M., Palekar, N., & Kim, M.-J. (2022). Potential of Transcranial Direct Current Stimulation in Alzheimer’s Disease: Optimizing Trials Toward Clinical Use. Journal of Clinical Neurology, 18(4), 391–400. https://doi.org/10.3988/jcn.2022.18.4.391 PDF
de Oliveira, P. C. A., de Araújo, T. A. B., Machado, D. G. da S., Rodrigues, A. C., Bikson, M., Andrade, S. M., Okano, A. H., Simplicio, H., Pegado, R., & Morya, E. (2022). Transcranial Direct Current Stimulation on Parkinson’s Disease: Systematic Review and Meta-Analysis. Frontiers in Neurology, 12. https://doi.org/10.3389/fneur.2021.794784 PDF
Stefano, L. H. S., Favoretto, D. B., Nascimento, D. C., Santos, L. R. A., Louzada, F., Bikson, M., Leite, J. P., Pontes-Neto, O. M., Edwards, D. J., & Edwards, T. G. (2022). Middle cerebral artery blood flow stability in response to high-definition transcranial electrical stimulation: A randomized sham-controlled clinical trial. Clinical Neurology and Neurosurgery, 220, 107345. https://doi.org/10.1016/j.clineuro.2022.107345 PDF
Antal, A., Luber, B., Brem, AK., Bikson, M., Brunoni, A. R., Kadosh, R. C., Dubljevic, V., Fecteau, S., Ferreri, F., Flöel, A., Hallett, M., Hamilton, R. H., Herrmann, C. S., Lavidor, M., Loo, C., Lustenberger, C., Machado, S., Miniussi, C., Moliadze, V., Nitsche, M. A., Rossi, S., Rossini, P. M., Santarnecchi, E., Seeck, M., Thut, G., Turi, Z., Ugawa, Y., Venkatasubramanian, G., Wenderoth, N., Wexler, A., Ziemann, U., & Paulus, W. (2022). Non-invasive brain stimulation and neuroenhancement, Clinical Neurophysiology Practice, 7, 146-165. https://doi.org/10.1016/j.cnp.2022.05.002 PDF
Salameh, A., McCabe, J., Skelly, M., Duncan, K. R., Chen, Z., Tatsuoka, C., Bikson, M., Hardin, E. C., Daly, J. J., & Pundik, S. (2022). Stance Phase Gait Training Post Stroke Using Simultaneous Transcranial Direct Current Stimulation and Motor Learning-Based Virtual Reality-Assisted Therapy: Protocol Development and Initial Testing. Brain Sciences, 12(6), 701. https://doi.org/10.3390/brainsci12060701 PDF
Quintiliano, A., Bikson, M., Oehmen, T., Pegado, R., Kirsztajn, G. M. (2022). Transcranial Direct Current Stimulation (tDCS): Pain Management in End-Stage Renal Disease - Report of an Early Randomized Controlled Trial. Journal of Pain and Symptom Management, 64(3), 234-243. https://doi.org/10.1016/j.jpainsymman.2022.05.018 PDF
Andrade, S. M., Silvestre, M. C. de A., de França, E. É. T., Queiroz, M. H. B. S., Santana, K. de J., Madruga, M. L. L. H., Mendes, C. K. T. T., de Oliveira, E. A., Bezerra, J. F., Barreto, R. G., da Silva, S. M. A. F., de Sousa, T. A., de Sousa, W. C. M., da Silva, M. P., Ribeiro, V. M. C., Lucena, P., Beltrammi, D., Catharino, R. R., Caparelli-Dáquer, E., Hampstead, B. M., Datta A., Teixeira, A. L., Fernandez-Calvo, B., Sato, J. R., & Bikson, M. (2022). Efficacy and safety of HD-tDCS and respiratory rehabilitation for critically ill patients with COVID-19 The HD-RECOVERY randomized clinical trial. Brain Stimulation: Basic, Translational, and Clinical Research in Neuromodulation, 15(3), 780–788. https://doi.org/10.1016/j.brs.2022.05.006 PDF
DaSilva, A. F., Datta, A., Swami, J., Kim, D. J., Patil, P. G., & Bikson, M. (2022). The Concept, Development, and Application of a Home-Based High-Definition tDCS for Bilateral Motor Cortex Modulation in Migraine and Pain. Frontiers in Pain Research, 3. https://doi.org/10.3389/fpain.2022.798056 PDF
Williams, P. T. J. A., Truong, D. Q., Seifert, A. C., Xu, J., Bikson, M., & Martin, J. H. (2022). Selective augmentation of corticospinal motor drive with trans-spinal direct current stimulation in the cat. Brain Stimulation: Basic, Translational, and Clinical Research in Neuromodulation, 15(3), 624–634. https://doi.org/10.1016/j.brs.2022.03.007 PDF
Baker, T. S., Zannou, A. L., Cruz, D., Khadka, N., Kellner, C., Tyc, R., Bikson, M., & Costa, A. (2022). Development and Clinical Validation of a Finite Element Method Model Mapping Focal Intracranial Cooling. IEEE Transactions on Neural Systems and Rehabilitation Engineering, 30, 2168-2174. https://doi.org/10.1109/TNSRE.2022.3161085 PDF
Khadka, N., & Bikson, M. (2022). Noninvasive Electrical Brain Stimulation of the Central Nervous System. Handbook of Neuroengineering, 1-33. https://doi.org/10.1007/978-981-15-2848-4_59-1 PDF
Jeong, H., Song, I.-U., Chung, Y.-A., Park, J.-S., Na, S.-H., Im, J. J., Bikson, M., Lee, W., & Yoo, S.-S. (2022). Short-Term Efficacy of Transcranial Focused Ultrasound to the Hippocampus in Alzheimer’s Disease: A Preliminary Study. Journal of Personalized Medicine, 12(2), 250. https://doi.org/10.3390/jpm12020250 PDF
Silva-Filho, E., Pilloni, G., Charvet, L. E., Fregni, F., Brunoni, A. R., & Bikson, M. (2022). Factors supporting availability of home-based Neuromodulation using remote supervision in middle-income countries; Brazil experience. Brain Stimulation: Basic, Translational, and Clinical Research in Neuromodulation, 15(2), 385–387. https://doi.org/10.1016/j.brs.2022.02.005 PDF
Cho, H., Razza, L. B., Borrione, L., Bikson, M., Charvet, L., Dennis-Tiwary, T. A., Brunoni, A. R., & Sudbrack-Oliveira, P. (2022). Transcranial Electrical Stimulation for Psychiatric Disorders in Adults: A Primer. Focus, 20(1), 19-31. https://doi.org/10.1176/appi.focus.20210020 PDF
2021
Cohen, S. L., Bikson, M., Badran, B. W., George, M. S. (2021). A visual and narrative timeline of US FDA milestones for Transcranial Magnetic Stimulation (TMS) devices. Brain Stimulation: Basic, Translational, and Clinical Research in Neuromodulation, 15(1), 73–75. https://doi.org/10.1016/j.brs.2021.11.010 PDF
Khadka, N., Bikson, M. (2021). Transcranial Electrical Stimulation (tES). The NeuroTech Primer: A Beginner’s Guide to Everything Neurotechnology, NeuroTechX. 109-125, ISBN: 979-8454254056 PDF
Sharma, M., Farahani, F., Bikson, M., Parra L. C. (2021). Weak DCS causes a relatively strong cumulative boost of synaptic plasticity with spaced learning. Brain Stimulation: Basic, Translational, and Clinical Research in Neuromodulation, 15(1), 57–62. https://doi.org/10.1016/j.brs.2021.10.552 PDF
Gebodh, N., Esmaeilpour, Z., Datta, A. & Bikson, M. (2021). Dataset of concurrent EEG, ECG, and behavior with multiple doses of transcranial electrical stimulation. Scientific Data, 8(1), 274. https://doi.org/10.1038/s41597-021-01046-y PDF
Truong, D. Q., Khadka, N., Peterchev, A. V. & Bikson, M. (2021). Transcranial electrical stimulation devices. The Oxford Handbook of Transcranial Stimulation, Second Edition. Oxford University Press. 2, 2-55. https://doi.org/10.1093/oxfordhb/9780198832256.013.2 PDF
Xia, Y., Li, Y., Khalid, W., Bikson, M., & Fu, B. M. (2021). Direct Current Stimulation Disrupts Endothelial Glycocalyx and Tight Junctions of the Blood-Brain Barrier in vitro. Frontiers in Cell and Developmental Biology, 9. https://doi.org/10.3389/fcell.2021.731028 PDF
Kreisberg, E., Esmaeilpour, Z., Adair D., Khadka, N., Datta, A., Badran. B. W., Douglas Bremner, J., Bikson, M. (2021). High-resolution computational modeling of the current flow in the outer ear during transcutaneous auricular Vagus Nerve Stimulation (taVNS). Brain Stimulation. 14, 1419 -1430. https://doi.org/10.1016/j.brs.2021.09.001 PDF
Farahani, F., Sharma, M., Parra, L.C., Bikson, M. (2021). Animal Models of tES: Methods, Techniques, and Safety. In: Brunoni A. R., Nitsche M. A., Loo C. K. (eds), Transcranial Direct Current Stimulation in Neuropsychiatric Disorders, 49-66. https://doi.org/10.1007/978-3-030-76136-3_4 PDF
Sharma, M., Farahani, F., Bikson, M., & Parra, L.C. (2021). Animal Studies on the Mechanisms of Low-Intensity Transcranial Electric Stimulation (eds), Transcranial Direct Current Stimulation in Neuropsychiatric Disorders, 67-92. https://doi.org/10.1007/978-3-030-76136-3_5 PDF
Jones, A. P., Goncalves-Garcia, M., Gibson B, Trumbo, M. C. S., Coffman, B. A., Robert B., Gill. H. A., Mullins, T., Hunter, M. A., Robinson, C. S. H., Combs, A., Khadka, N., Bikson, M., Clark, V. P. (2021). Investigating the brain regions involved in tDCS-Enhanced category learning using finite element modeling. Neuroimage: Reports. 1(4), 100048. https://doi.org/10.1016/j.ynirp.2021.100048 PDF
Unal, G., Swami, J. K., Canela, C., Cohen, S. L., Khadka, N., FallahRad, M., Short, B., Argyelan, M., Sackeim, H. A., & Bikson, M. (2021). Adaptive current-flow models of ECT: Explaining individual static impedance, dynamic impedance, and brain current density. Brain Stimulation. 14(5), 1154-1168. https://doi.org/10.1016/j.brs.2021.07.012 PDF
da Silva Machado, D. G., Bikson, M., Datta, A., Caparelli-Dáquer, E., Unal, G., Baptista, A. F., Cyrino, E. S., Li, L. M., Morya, E., Moreira, A., & Okano, A. H. (2021). Acute effect of high-definition and conventional tDCS on exercise performance and psychophysiological responses in endurance athletes: A randomized controlled trial. Scientific Reports, 11(1), 13911. https://doi.org/10.1038/s41598-021-92670-6 PDF
Bahr-Hosseini, M., & Bikson, M. (2021). Neurovascular-modulation: A review of primary vascular responses to transcranial electrical stimulation as a mechanism of action. Brain Stimulation, 14(4), 837-847. https://doi.org/10.1016/j.brs.2021.04.015 PDF
Moreira, A., Machado, D. G. da S., Bikson, M., Unal, G., Bradley, P. S., Moscaleski, L., Costa, T., Kalil, G. C. S. G., Chao, L. W., Baptista, A. F., Morya, E., & Okano, A. H. (2021). Effect of Transcranial Direct Current Stimulation on Professional Female Soccer Players’ Recovery Following Official Matches. Perceptual and Motor Skills, 128(4), 1504–1529. https://doi.org/10.1177/00315125211021239
Myruski, S., Cho, H., Bikson, M., & Dennis-Tiwary, T. A. (2021). Transcranial Direct Current Stimulation (tDCS) Augments the Effects of Gamified, Mobile Attention Bias Modification. Front Neuroergonomics, 2.https://doi.org/10.3389/fnrgo.2021.652162 PDF
Farmer, A. D., Strzelczyk, A., Finisguerra, A., Gourine, A. V., Gharabaghi, A., Hasan, A., Burger, A. M., Jaramillo, A. M., Mertens, A., Majid, A., Verkuil, B., Badran, B. W., Ventura-Bort, C., Gaul, C., Beste, C., Warren, C. M., Quintana, D. S., Hämmerer, D., Freri, E., Frangos, E., Tobaldini, E., Kaniusas, E., Rosenow, F., Capone, F., Panetsos, F., Ackland, G. L., Kaithwas, G., O'Leary, G. H., Genheimer, H., Jacobs, H. I. L., Van Diest, I., Schoenen, J., Redgrave, J., Fang, J., Deuchars, J., Széles, J. C., Thayer, J. F., More, K., Vonck, K., Steenbergen, L., Vianna, L.C., McTeague, L. M., Ludwig, M., Veldhuizen, M. G., De Couck, M., Casazza, M., Keute, M., Bikson, M., Andreatta, M., D'Agostini, M., Weymar, M., Betts, M., Prigge, M., Kaess, M., Roden, M., Thai, M., Schuster, N. M., Montano, N., Hansen, N., Kroemer, N. B., Rong, P., Fischer, R., Howland, R. H., Sclocco, R., Sellaro, R., Garcia, R. G., Bauer, S., Gancheva, S., Stavrakis, S., Kampusch, S., Deuchars, S. A., Wehner, S., Laborde, S., Usichenko, T., Polak, T., Zaehle, T., Borges, U., Teckentrup, V., Jandackova, V. K., Napadow, V. & Koenig, J. (2021) International Consensus Based Review and Recommendations for Minimum Reporting Standards in Research on Transcutaneous Vagus Nerve Stimulation (Version 2020). Frontiers in Human Neuroscience, 14. https://doi.org/10.3389/fnhum.2020.568051 PDF
De Souza, C. G., Pegado, R., Costa, J. F., Morya, E., Baptista, A., Unal, G., Bikson, M., & Okano, A. H. (2021). Alternate sessions of transcranial direct current stimulation (tDCS) reduce chronic pain in women affected by chikungunya. A randomized clinical trial. Brain Stimulation, 14(3), 541-548. https://doi.org/10.1016/j.brs.2021.02.015 PDF
Moreira, A., Machado, D. G. da S., Moscaleski, L., Bikson, M., Unal, G., Bradley, P. S., Baptista, A. F., Morya, E., Cevada, T., Marques, L., Zanetti, V., & Okano, A. H. (2021). Effect of tDCS on well-being and autonomic function in professional male players after official soccer matches. Physiology & Behavior, 233(1), 113351. https://doi.org/10.1016/j.physbeh.2021.113351 PDF
Sehatpour, P., Dondé, C., Adair, D., Kreither, J., Lopez-Calderon, J., Avissar, M., Bikson, M., & Javitt, D. C. (2021). Comparison of cortical network effects of high-definition and conventional tDCS during visuomotor processing. Brain Stimulation, 14(1), 33-35. https://doi.org/10.1016/j.brs.2020.11.004 PDF
2020
Ghobadi-Azbari, P., Jamil, A., Yavari, F., Esmaeilpour, Z., Malmir, N., Mahdavifar-Khayati, R., Soleimani, G., Cha, Y. H., Shereen, A. D., Nitsche, M. A., Bikson, M., & Ekhtiari, H. (2020). fMRI and transcranial electrical stimulation (tES): A systematic review of parameter space and outcomes. Progress in Neuropsychopharmacology and Biological Psychiatry 107, 110149. https://doi.org/10.1016/j.pnpbp.2020.110149 PDF
Khadka, N. & Bikson, M. (2020). Neurocapillary-modulation. Neuromodulation: Technology at the Neural Interface. https://doi.org/10.1111/ner.13338 PDF
Esmaeilpour, Z., Jackson, M., Kronberg, G., Zhang, T., Esteller, R., Hershey B., & Bikson, M. (2020) Limited sensitivity of hippocampal synaptic function or network oscillations to unmodulated kilohertz electric fields. eNeuro, 368(20). https://doi.org/10.1523/ENEURO.0368-20.2020 PDF
Baptista, A. F., Baltar, A., Okano, A. H., Moreira, A., Campos, A. C. P., Fernandes, A. M., Brunoni, Badran, B. W., Tanaka, C., Ciampi de Andrade, D., Machado, D. G. da S., Morya, E., Trujillo, E., Swami, J. K., Camprodon, J. A., Monte-Silva, K., Sá, K. N., Nunes, I., Goulardins, J. B., Bikson, M., Sudbrack-Oliveira, P., de Carvalho, P., Duarte-Moreira, R. J., Pagano, R. L., Shinjo, S. K., & Zana, Y. (2020). Applications of Non-invasive Neuromodulation for the Management of Disorders Related to COVID-19. Frontiers in Neurology, 11(573718). https://doi.org/10.3389/fneur.2020.573718 PDF
Khadka, N., & Bikson, M. (2020). Role of skin tissue layers and ultra-structure in transcutaneous electrical stimulation including tDCS. Physics in Medicine &Biology, 65(22). https://doi.org/10.1088/1361-6560/abb7c1 PDF
Rossi, S., Antal, A., Bestmann, S., Bikson, M., Brewer, C., Brockmöller, J., Carpenter, L. L., Cincotta, M., Chen, R., Daskalakis, J. D., Di Lazarro, V., Fox, M. D., George, M. S., Gilbert, D., Kimiskidis, V. K., Koch, G., Ilmoniemi, R. J., Lefaucheur, J. P., Leocani, L., Lisanby, S. H., Miniussi, C., Padberg, F., Pascual-Leone, A., Paulus, W., Peterchev, A. V., Quartarone, A., Rotenberg, A., Rothwell, J., Rossini, P. M., Santarnecchi, E., Shafi, M. M., Siebner, H. R., Ugawa, Y., Wassermann, E. M., Zangen, A., Ziemann, U., & Hallett, M. (2020). Safety and recommendations for TMS use in healthy subjects and patient populations, with updates on training, ethical and regulatory issues: Expert guidelines. Clinical Neurophysiology, 132(1), 269-306. https://doi.org/10.1016/j.clinph.2020.10.003 PDF
Esmaeilpour, Z., Kronberg, G., Reato, D., Parra, L.C., & Bikson, M. (2020). Temporal interference stimulation targets deep brain regions by modulating neural oscillations. Brain Stimulation, 11(7). https://doi.org/10.1016/j.brs.2020.11.007 PDF
Vaclavik, D., Bechor, M., Foster, A., Gralnik, L.M., Bar-Haim, Y., Pine, D.S., Bikson, M., Silverman, W.K., Reeb-Sutherland, B.C., & Pettit, J.W. (2020). Case series of transcranial direct current stimulation as an augmentation strategy for attention bias modification training in adolescents with anxiety disorders. Clinical Psychology and Special Education, 9(3), 105-126. https://doi.org/10.17759/cpse.2020090308 PDF
Xia, Y., Khalid, W., Yin, Z., Huang, G., Bikson, M., & Fu, B.M. (2020). Modulation of solute diffusivity in brain tissue as a novel mechanism of transcranial direct current stimulation (tDCS). Scientific Reports, 10, 18488. https://doi.org/10.1038/s41598-020-75460-4 PDF
Truong, D.Q., Khadka, N., & Bikson, M. (2020). Transcranial Electrical Stimulation. In: He B. (eds) Neural Engineering. Springer Cham. https://doi.org/10.1007/978-3-030-43395-6 PDF
Bremner, J.D., Gurel, N. Z., Wittbrodt, M.T., Shandhi, M.H., Rapaport, M.H., Nye, J.A., Pearce, B.D., Vaccarino, V., Shah, A.J., Park, J., Bikson, M., & Inan, O.T. (2020). Application of noninvasive vagal nerve stimulation to stress-related psychiatric disorders. Journal of Personalized Medicine, 10(3), 1-25. https://doi.org/10.3390/jpm10030119 PDF
Jiang, J., Truong, D. Q., Esmaeilpour, Z., Huang, Y., Badran, B. W., & Bikson, M. (2020). Enhanced tES and tDCS computational models by meninges emulation. Journal of Neural Engineering, 17(1). https://doi.org/10.1088/1741-2552/ab549d Full PubMED Article PDF
Rajji, T. K., Bowie, C. R., Herrmann, N., Pollock, B. G., Bikson, M., Blumberger, D. M., Butters, M. A., Daskalakis, Z. J., Fischer, C. E., Flint, A. J., Golas, A. C., Graff-Guerrero, A., Kumar, S., Lourenco, L., Mah, L., Ovaysikia, S., Thorpe, K. E., Voineskos, A. N., & Mulsant, B. H. (2020). Design and rationale of the PACt-MD randomized clinical trial: Prevention of alzheimer's dementia with cognitive remediation plus transcranial direct current stimulation in mild cognitive impairment and depression. Journal of Alzheimer's Disease, 76(2), 733-751. https://doi.org/10.3233/JAD-200141
Fregni, F., El-Hagrassy, M. M., Pacheco-Barrios, K., Carvalho, S., Leite, J., Simis, M., Brunelin, J., Nakamura-Palacios, E. M., Marangolo, P., Venkatasubramanian, G., San-Juan, D., Caumo, W., Bikson, M., Brunoni, A. R., & Neuromodulation Center Working Group (2020). Evidence-based guidelines and secondary meta-analysis for the use of transcranial direct current stimulation (tDCS) in neurological and psychiatric disorders. The International Journal of Neuropsychopharmacology, 24(4), 256–313. https://doi.org/10.1093/ijnp/pyaa051 PDF
Adusumilli, P. S., Bikson, M., Rizk, N. P., Rusch, V. W., Hristov, B., Grosser, R., Tan, K. S., Sarkaria, I. S., Huang, J., Molena, D., Jones, D. R., & Bains, M. S. (2020). A prospective trial of intraoperative tissue oxygenation measurement and its association with anastomotic leak rate after Ivor Lewis esophagectomy. Journal of Thoracic Disease, 12(4), 1449-1459. http://dx.doi.org/10.21037/jtd.2020.02.58 PDF
Bikson, M., Hanlon, C. A., Woods, A. J., Gillick, B. T., Charvet, L., Lamm, C., Madeo, G., Holczer, A., Almeida, J., Antal, A., Ay, M. R., Baeken, C., Blumberger, D. M., Campanella, S., Camprodon, J. A., Christiansen, Loo, C., Crinion, J. T., Fitzgerald, P., Gallimberti, L., Ghobadi-Azbari, P., Ghodratitoostani, I., Grabner, R. H., Hartwigsen, G., Hirata, A., Kirton, A., Knotkova, H., Kruptisky, E., Marangolo, P., Nakamura-Palacios, E. M., Potok, W., Praharaj, S. K., Ruff, C. C., Schlaug, G., Siebner, H. R., Stagg, C. J., Thielscher, A., Wenderoth, N., Yuan, T.-F., Zhang, X., & Ekhtiari, H. (2020). Guidelines for TMS/tES clinical services and research through the COVID-19 pandemic. Brain Stimulation, 13(4), 1124-1149. https://doi.org/10.1016/j.brs.2020.05.010 online PDF
Caulfield, K. A., Badran, B. W., Li, X., Bikson, M., & George, M. S. (2020). Can transcranial electrical stimulation motor threshold estimate individualized tDCS doses over the prefrontal cortex? Evidence from reverse-calculation electric field modeling. Brain Stimulation, 13(4), 1150-1152. https://doi.org/10.1016/j.brs.2020.05.012 PDF
Caulfield, K. A., Badran, B. W., DeVries, W. H., Summers, P. M., Kofmehl, E., Li, X., Borckardt, J. J., Bikson, M., & George, M. S. (2020). Transcranial electrical stimulation motor threshold can estimate individualized tDCS dosage from reverse-calculation electric-field modeling. Brain Stimulation, 13(4), 961-969. https://doi.org/10.1016/j.brs.2020.04.007 PDF
Jog, M., Jann, K., Yan, L., Huang, Y., Parra, L., Narr, K., Bikson, M., & Wang, D. J. J. (2020). Concurrent imaging of markers of current flow and neurophysiological changes during tDCS. Frontiers in Neuroscience, 14. https://doi.org/10.3389/fnins.2020.00374 PDF
Charvet, L. E., Shaw, M. T., Bikson, M., Woods, A. J., & Knotkova, H. (2020). Supervised transcranial direct current stimulation (tDCS) at home: A guide for clinical research and practice. Brain Stimulation, 13(3), 686-693. https://doi.org/10.1016/j.brs.2020.02.011 PDF
Khadka, N., Liu, X., Zander, H., Swami, J., Rogers, E., Lempka, S. F., & Bikson, M. (2020). Realistic anatomically detailed open-source spinal cord stimulation (RADO-SCS) model. Journal of Neural Engineering, 17(2). https://doi.org/10.1088/1741-2552/ab8344 PDF
Adair, D., Truong, D., Esmaeilpour, Z., Gebodh, N., Borges, H., Ho, L., Bremner, J. D., Badran, B. W., Napadow, V., Clark, V. P., & Bikson, M. (2020). Electrical stimulation of cranial nerves in cognition and disease. Brain Stimulation, 13(3), 717-750. https://doi.org/10.1016/j.brs.2020.02.019 PDF
Cook, D. N., Thompson, S., Stomberg-Firestein, S., Bikson, M., George, M. S., Jenkins, D. D., & Badran, B. W. (2020). Design and validation of a closed-loop, motor-activated auricular vagus nerve stimulation (MAAVNS) system for neurorehabilitation. Brain Stimulation, 13(3), 800-803. https://doi.org/10.1016/j.brs.2020.02.028 PDF
Badran, B. W., Jenkins, D. D., Cook, D., Thompson, S., Dancy, M., DeVries, W. H., Mappin, G., Summers, P., Bikson, M., & George, M. S. (2020). Transcutaneous auricular vagus nerve stimulation-paired rehabilitation for oromotor feeding problems in newborns: An open-label pilot study. Frontiers in Human Neuroscience, 14. https://doi.org/10.3389/fnhum.2020.00077 PDF
Unal, G., Ficek, B., Webster, K., Shahabuddin, S., Truong, D., Hampstead, B., Bikson, M., & Tsapkini, K. (2020). Impact of brain atrophy on tDCS and HD-tDCS current flow: a modeling study in three variants of primary progressive aphasia. Neurological sciences: official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 41(7), 1781–1789. https://doi.org/10.1007/s10072-019-04229-z PDF
Khadka, N., Harmsen, I. E., Lozano, A. M., & Bikson, M. (2020). Bio-heat model of kilohertz-frequency deep brain stimulation increases brain tissue temperature. Neuromodulation, 23(4), 489-495. https://doi.org/10.1111/ner.13120 PDF
Shin, D. W., Fan, J., Luu, E., Khalid, W., Xia, Y., Khadka, N., Bikson, M., & Fu, B. M. (2020). In vivo modulation of the Blood–Brain barrier permeability by transcranial direct current stimulation (tDCS). Annals of Biomedical Engineering, 48(4), 1256-1270. https://doi.org/10.1007/s10439-020-02447-7 PDF
Kronberg, G., Rahman, A., Sharma, M., Bikson, M., & Parra, L. C. (2020). Direct current stimulation boosts hebbian plasticity in vitro. Brain Stimulation, 13(2), 287-301. https://doi.org/10.1016/j.brs.2019.10.014 PDF
Lazarev, V. V., Gebodh, N., Tamborino, T., Bikson, M., & Caparelli-Daquer, E. M. (2020). Experimental-design specific changes in spontaneous EEG and during intermittent photic stimulation by high definition transcranial direct current stimulation. Neuroscience, 426, 50-58. https://doi.org/10.1016/j.neuroscience.2019.11.016. PDF
Bikson, M., & Dmochowski, J. (2020). What it means to go deep with non-invasive brain stimulation. Clinical Neurophysiology, 131(3), 752-754. https://doi.org/10.1016/j.clinph.2019.12.003 PDF
Esmaeilpour, Z., Shereen, A. D., Ghobadi-Azbari, P., Datta, A., Woods, A. J., Ironside, M., O’Shea, J., Kirk, U., Bikson, M., & Ekhtiari, H. (2020). Methodology for tDCS integration with fMRI. Human Brain Mapping, 41(7), 1950-1967. http://dx.doi.org/10.1002/hbm.24908 PDF
Koganemaru, S., Mikami, Y., Matsuhashi, M., Truong, D. Q., Bikson, M., Kansaku, K., & Mima, T. (2020). Cerebellar transcranial alternating current stimulation modulates human gait rhythm. Neuroscience Research, 156, 265-270. http://dx.doi.org/10.1016/j.neures.2019.12.003. PDF
Khadka, N., Borges, H., Paneri, B., Kaufman, T., Nassis, E., Zannou, A. L., Shin, Y., Choi, H., Kim, S., Lee, K., & Bikson, M. (2020). Adaptive current tDCS up to 4 mA. Brain Stimulation, 13(1), 69-79. https://doi.org/10.1016/j.brs.2019.07.027 PDF
2019
Borges, H., Dufau, A., Paneri, B., Woods, A. J., Knotkova, H., & Bikson, M. (2019). Updated technique for reliable, easy, and tolerated transcranial electrical stimulation including transcranial direct current stimulation. Journal of Visualized Experiments, 2020(155). https://doi.org/10.3791/59204 PDF
Khadka, N., & Bikson, M. (2019). Response to the letter to the editor by caraway et al. on “Tissue temperature increases by a 10 kHz spinal cord stimulation system: Phantom and bioheat model”. Neuromodulation, 22(8), 988. https://doi.org/10.1111/ner.13079. PDF
Sivaramakrishnan, A., Datta, A., Bikson, M., & Madhavan, S. (2019). Remotely supervised transcranial direct current stimulation: A feasibility study for amyotrophic lateral sclerosis. NeuroRehabilitation, 45(3), 369-378. http://doi.org/10.3233/NRE-192851.
Morya, E., Monte-Silva, K., Bikson, M., Esmaeilpour, Z., Biazoli, C. E., Jr., Fonseca, A., Bocci, T., Farzan, F., Chatterjee, R., Hausdorff, J. M., Machado, D. G. da S., Brunoni, A. R., Mexger, E., Moscaleski, L. A., Pegado, R., Sato, J. R., Caetano, M. S., Sá, K. N., Tanaka, C., Li, L. M., Baptiste, A. F., & Okano, A. H. (2019). Beyond the target area: An integrative view of tDCS-induced motor cortex modulation in patients and athletes. Journal of NeuroEngineering and Rehabilitation, 16(1). https://doi.org/10.1186/s12984-019-0581-1 PDF
Argyelan, M., Oltedal, L., Deng, Z. -., Wade, B., Bikson, M., Joanlanne, A., Sanghani, S., Bartsch, H., Cano, M., Dale, A. M., Dannlowski, U., Dols, A., Enneking, V., Espinoza, R., Kessler, U., Narr, K. L., Oedegaard, K. L., Oudega, M. L., Redlich, R., Stek, M. L., Takamiya, A., Emsell, L., Bouckaert, F., Sienaert, P., Pujol, J., Indira, Tendolkar, I., van Eijndhoven, P., Petrides, G., Malhotra, A. K., & Abbott, C. (2019). Electric field causes volumetric changes in the human brain. ELife, 8. https://doi.org/10.7554/eLife.49115 PDF
Khadka, N., Truong, D. Q., Williams, P., Martin, J. H., & Bikson, M. (2019). The quasi-uniform assumption for spinal cord stimulation translational research. Journal of Neuroscience Methods, 328 https://doi.org/10.1016/j.jneumeth.2019.108446 PDF
Hosseini, M. B., Hou, J., Bikson, M., Iacoboni, M., Gornbein, J., & Saver, J. L. (2019). Central nervous system electrical stimulation for neuroprotection in acute cerebral ischemia meta-analysis of preclinical studies. Stroke, 50(10), 2892-2901. https://doi.org/10.1161/STROKEAHA.119.025364 PDF
Bikson, M., Esmaeilpour, Z., Adair, D., Kronberg, G., Tyler, W. J., Antal, A., Datta, A., Sabel, B. A., Nitsche, M. A., Loo, C., Edwards, D., Ekhtiari, H., Knotkova, H., Woods, A. J., Hampstead, B. M., Badran, B. W., & Peterchev, A. V. (2019). Transcranial electrical stimulation nomenclature. Brain Stimulation, 12(6), 1349-1366. https://doi.org/10.1016/j.brs.2019.07.010 PDF
Seibt, O., Truong, D., Khadka, N., Huang, Y., & Bikson, M. (2019) Computational Finite Element Method (FEM) forward modeling workflow for transcranial Direct Current Stimulation (tDCS) current flow on MRI-derived head: Simpleware and COMSOL Multiphysics tutorial. bioRxiv, 704940. https://doi.org/10.1101/704940 PDF
Valero-Cabré, A., Sanches, C., Godard, J., Fracchia, O., Dubois, B., Levy, R., Truong, D. Q., Bikson, M., & Teichmann, M. (2019). Language boosting by transcranial stimulation in progressive supranuclear palsy. Neurology, 93(6), E537-E547. https://doi.org/10.1212/WNL.0000000000007893 PDF
Ekhtiari, H., Tavakoli, H., Addolorato, G., Baeken, C., Bonci, A., Campanella, S., Castelo-Branco, L., Challet-Bouju, G., Clark, V. P., Claus, E., Dannon, P. N., Felice, A. D., den Uyl, T., Diana, M., di Giannantonio, M., Fedota, J. R., Fitzgerald, P., Gallimberti, L., Grall-Bronnec, M., Herremans, S. C., Herrmann, M. J., Jamil, A., Khedr, E., Kouimtsidis, C., Kozak, K., Krupitsky, E., Lamm, C., Lechner, W. V., Madeo, G., Malmir, N., Martinotti, G., McDonald, W. M., Montemitro, C., Nakamura-Palacios, E. M., Nasehi, M., Nöel, X., Nosratabadi, M., Paulus, M., Pettorusso, M., Pradhan, B., Praharaj, S. K., Rafferty, H., Sahlem, G., jo Salmeron, B., Sauvaget, A., Schluter, R. S., Sergiou, C., Shahbabaie, A., Sheffer, C., Spagnolo, P. A., Steele, V. R., Yuan, T.-F., van Dongen, J. D. M., Waes, V. V., Venkatasubramanian, G., Verdejo-García, A., Verveer, I., Welsh, J. W., Wesley, M. J., Witkiewitz, K., Yavari, F., Zarrindast, M.-R., Zawertailo, L., Zhang, X., Cha, Y.-H., George, T. P., Frohlich, F., Goudriaan, A. E., Fecteau, S., Daughters, S. B., Stein, E. A., Fregni, F., Nitsche, M. A., Zangen, A., Bikson, M., & Hanlon, C. A. (2019). Transcranial electrical and magnetic stimulation (tES and TMS) for addiction medicine: A consensus paper on the present state of the science and the road ahead. Neuroscience and Biobehavioral Reviews, 104, 118-140. https://doi.org/10.1016/j.neubiorev.2019.06.007 PDF
Im, J. J., Jeong, H., Bikson, M., Woods, A. J., Unal, G., Oh, J. K., Na, S., Park, J.-S., Knotkova, H., Song, I.-U., & Chung, Y. -. (2019). Effects of 6-month at-home transcranial direct current stimulation on cognition and cerebral glucose metabolism in alzheimer's disease. Brain Stimulation, 12(5), 1222-1228. https://doi.org/10.1016/j.brs.2019.06.003 PDF
Meiron, O., Gale, R., Namestnic, J., Bennet-Back, O., Gebodh, N., Esmaeilpour, Z., Mandzhiyev, V., & Bikson, M. (2019). Antiepileptic effects of a novel noninvasive neuromodulation treatment in a subject with early-onset epileptic encephalopathy: Case report with 20 sessions of HDTDCS intervention. Frontiers in Neuroscience, 13(MAY). https://doi.org/10.3389/fnins.2019.00547 PDF
Ambrose-Zaken, G. V., FallahRad, M., Bernstein, H., Wall Emerson, R., & Bikson, M. (2019). Wearable cane and app system for improving mobility in Toddlers/Pre-schoolers with visual impairment. Frontiers in Education, 4. https://doi.org/10.3389/feduc.2019.00044 PDF
Zannou, A. L., Khadka, N., FallahRad, M., Truong, D. Q., Kopell, B. H., & Bikson, M. (2019). Tissue temperature increases by a 10 kHz spinal cord stimulation system: Phantom and bioheat model. Neuromodulation, 24(8), 1327-1335.https://doi.org/10.1111/ner.12980 PDF
Huang, Y., Datta, A., Bikson, M., & Parra, L. C. (2019). Realistic volumetric-approach to simulate transcranial electric stimulation - ROAST - a fully automated open-source pipeline. Journal of Neural Engineering, 16(5). https://doi.org/10.1088/1741-2552/ab208d PDF Support and Documentation here
FallahRad, M., Zannou, A. L., Khadka, N., Prescott, S. A., Ratté, S., Zhang, T., Esteller, R., Hershey, B., & Bikson, M. (2019). Electrophysiology equipment for reliable study of kHz electrical stimulation. Journal of Physiology, 597(8), 2131-2137. https://doi.org/10.1113/JP277654 PDF
Lattari, E., Vieira, L. A. F., Oliveira, B. R. R., Unal, G., Bikson, M., De Mello Pedreiro, R. C., Neto, S. R. M., Machado, S., & Maranhaõ-Neto, G. A. (2019). Effects of transcranial direct current stimulation with caffeine intake on muscular strength and perceived exertion. Journal of Strength and Conditioning Research, 33(5), 1237-1243. https://doi.org/10.1519/JSC.0000000000003123 PDF
Hadar, R., Winter, R., Edemann-Callesen, H., Wieske, F., Habelt, B., Khadka, N., Felgel-Farnholz, V., Barroeta-Hlusicka, E., Reis, J., Tatarau, C. A., Funke, K., Fritsch, B., Bernhardt, N., Bikson, M., Nitsche, M. A., Winter, C. (2019). Prevention of schizophrenia deficits via non-invasive adolescent frontal cortex stimulation in rats. Molecular Psychiatry, 25(4), 896-905. https://doi.org/10.1038/s41380-019-0356-x PDF
Khadka, N., Woods, A. J., & Bikson, M. (2019) Transcranial Direct Current Stimulation Electrodes. In: Knotkova H., Nitsche M., Bikson M., Woods A. (eds) Practical Guide to Transcranial Direct Current Stimulation. Springer, Cham. https://doi.org/10.1007/978-3-319-95948-1_10 PDF
Fonteneau, C., Mondino, M., Arns, M., Baeken, C., Bikson, M., Brunoni, A. R., Burke, M. J., Neuvonen, T., Padberg, F., Pascual-Leone, A., Poulet, E., Ruffini, G., Santarnecchi, E., Sauvaget, A., Schellhorn, K., Suaud-Chagny, M.-F., Palm, U., & Brunelin, J. (2019). Sham tDCS: A hidden source of variability? reflections for further blinded, controlled trials. Brain Stimulation, 12(3), 668-673. https://doi.org/10.1016/j.brs.2018.12.977 PDF
Knotkova, H., Riggs, A., Berisha, D., Borges, H., Bernstein, H., Patel, V., Truong, D. Q., Unal, G., Arce, D., Datta, A., & Bikson, M. (2019). Automatic M1-SO montage headgear for transcranial direct current stimulation (TDCS) suitable for home and high-throughput in-clinic applications. Neuromodulation, 22(8), 904-910. https://doi.org/10.1111/ner.12786 PDF
Zannou, A. L., Khadka, N., Truong, D. Q., Zhang, T., Esteller, R., Hershey, B., & Bikson, M. (2019). Temperature increases by kilohertz frequency spinal cord stimulation. Brain Stimulation, 12(1), 62-72. https://doi.org/10.1016/j.brs.2018.10.007 PDF
Gebodh, N., Esmaeilpour, Z., Adair, D., Chelette, K., Dmochowski, J., Woods, A. J., Kappenman, E. S., Parra, L. C., & Bikson, M. (2019). Inherent physiological artifacts in EEG during tDCS. NeuroImage, 185, 408-424. https://doi.org/10.1016/j.neuroimage.2018.10.025 PDF
Badran, B. W., Yu, A. B., Adair, D., Mappin, G., DeVries, W. H., Jenkins, D. D., & George, M. S. (2019). Laboratory administration of transcutaneous auricular vagus nerve stimulation (taVNS): Technique, targeting, and considerations. Journal of Visualized Experiments, 2019(143). https://doi.org/10.3791/58984 PDF
2018
Machado, D. G. da S., Unal, G., Andrade S. M., Moreira, A., Altimari, L. R., Brunoni, A. R., Perrey, S., Mauger, A. R., Bikson, M., & Okano, A. H. (2018). Effect of transcranial direct current stimulation on exercise performance: A systematic review and meta-analysis. Brain Stimulation. 12(3), 593–605. https://doi.org/10.1016/j.brs.2018.12.227 PDF
Dobbs, B., Pawlak, N., Biagioni, M., Agarwal, S., Shaw, M., Pilloni, G., Bikson, M., Datta, A., & Charvet, L. (2018). Generalizing remotely supervised transcranial direct current stimulation (tDCS): Feasibility and benefit in parkinson's disease. Journal of NeuroEngineering and Rehabilitation, 15(1). https://doi.org/10.1186/s12984-018-0457-9 PDF
Marron, E. M., Viejo-Sobera, R., Cuatrecasas, G., Redolar-Ripoll, D., Lorda, P. G., Datta, A., Bikson, M., Magerowski, G., & Alonso-Alonso, M. (2018). Prefronto-cerebellar neuromodulation affects appetite in obesity. International Journal of Obesity, 43(10), 2119-2124. https://doi.org/10.1038/s41366-018-0278-8 PDF
Lee, S. H., Im, J. J., Oh, J. K., Choi, E. K., Yoon, S., Bikson, M., Song, I.-U., Jeong, H., & Chung, Y. -. (2018). Transcranial direct current stimulation for online gamers: A prospective single-arm feasibility study. Journal of Behavioral Addictions, 7(4), 1166-1170. https://doi.org/10.1556/2006.7.2018.107 PDF
Silva-Filho, E., Okano, A. H., Morya, E., Albuquerque, J., Cacho, E., Unal, G., Bikson, M., & Pegado, R. (2018). Neuromodulation treats chikungunya arthralgia: A randomized controlled trial. Scientific Reports, 8(1). https://doi.org/10.1038/s41598-018-34514-4 PDF
Santos, T. E. G., Favoretto, D. B., Toostani, I. G., Nascimento, D. C., Rimoli, B. P., Bergonzoni, E., Lemos, T. W., Truong, D. Q., Delbem, A. C. B., Makkiabadi, B., Moraes, R., Louzada F., Bikson, M., Leite, J. P., & Edwards, D. J. (2018). Manipulation of human verticality using high-definition transcranial direct current stimulation. Frontiers in Neurology, 9(OCT). https://doi.org/10.3389/fneur.2018.00825 PDF
Truong, D. Q., & Bikson, M. (2018). Physics of transcranial direct current stimulation devices and their history. Journal of ECT, 34(3), 137-143. https://doi.org/10.1097/YCT.0000000000000531 PDF
Khadka, N., Borges, H., Zannou, A. L., Jang, J., Kim, B., Lee, K., & Bikson, M. (2018). Dry tDCS: Tolerability of a novel multilayer hydrogel composite non-adhesive electrode for transcranial direct current stimulation. Brain Stimulation, 11(5), 1044-1053. https://doi.org/10.1016/j.brs.2018.07.049 PDF
Badran, B. W., Jenkins, D. D., DeVries, W. H., Dancy, M., Summers, P. M., Mappin, G. M., Bernstein, H., Bikson, M., Coker-Bolt, P., & George, M. S. (2018). Transcutaneous auricular vagus nerve stimulation (taVNS) for improving oromotor function in newborns. Brain Stimulation, 11(5), 1198-1200. https://doi.org/10.1016/j.brs.2018.06.009 PDF
Cancel, L. M., Arias, K., Bikson, M., & Tarbell, J. M. (2018). Direct current stimulation of endothelial monolayers induces a transient and reversible increase in transport due to the electroosmotic effect. Scientific Reports, 8(1). https://doi.org/10.1038/s41598-018-27524-9 PDF
Badran, B. W., Brown, J. C., Dowdle, L. T., Mithoefer, O. J., LaBate, N. T., Coatsworth, J., DeVries, W. H., Austelle, C. W., McTeague, L. M., Yu, A., Bikson, M., Jenkins, D. D., & George, M. S. (2018). Tragus or cymba conchae? investigating the anatomical foundation of transcutaneous auricular vagus nerve stimulation (taVNS). Brain Stimulation, 11(4), 947-948. https://doi.org/10.1016/j.brs.2018.06.003 PDF
Huh, Y., Jung, D., Seo, T., Sun, S., Kim, S. H., Rhim, H., Chung, S., Kim, C.-H., Kwon, Y., Bikson, M., Chung, Y.-, Kim, J. J., & Cho, J. (2018). Brain stimulation patterns emulating endogenous thalamocortical input to parvalbumin-expressing interneurons reduce nociception in mice. Brain Stimulation, 11(5), 1151-1160. https://doi.org/10.1016/j.brs.2018.05.007 PDF
Reckow, J., Rahman-Filipiak, A., Garcia, S., Schlaefflin, S., Calhoun, O., DaSilva, A. F., Bikson, M., & Hampstead, B. M. (2018). Tolerability and blinding of 4x1 high-definition transcranial direct current stimulation (HD-tDCS) at two and three milliamps. Brain Stimulation, 11(5), 991-997. https://doi.org/10.1016/j.brs.2018.04.022 PDF
Riggs, A., Patel, V., Paneri, B., Portenoy, R. K., Bikson, M., & Knotkova, H. (2018). At-home transcranial direct current stimulation (tDCS) with telehealth support for symptom control in chronically-ill patients with multiple symptoms. Frontiers in Behavioral Neuroscience, 12. https://doi.org/10.3389/fnbeh.2018.00093 PDF
Chhatbar, P. Y., Kautz, S. A., Takacs, I., Rowland, N. C., Revuelta, G. J., George, M. S., Bikson, M., & Feng, W. (2018). Evidence of transcranial direct current stimulation-generated electric fields at subthalamic level in human brain in vivo. Brain Stimulation, 11(4), 727-733. https://doi.org/10.1016/j.brs.2018.03.006 PDF
Bikson, M., Ruiz-Nuño, A., Miranda, D., Kronberg, G., Jiruska, P., Fox, J. E., & Jefferys, J. G. (2018). Synaptic transmission modulates while non-synaptic processes govern the transition from pre-ictal to seizure activity in vitro. bioRxiv, 280321. https://doi.org/10.1101/280321 PDF
Lee, W. H., Kennedy, N. I., Bikson, M., & Frangou, S. (2018). A computational assessment of target engagement in the treatment of auditory hallucinations with transcranial direct current stimulation. Frontiers in Psychiatry, 9(FEB). https://doi.org/10.3389/fpsyt.2018.00048 PDF
Edemann-Callesen, H., Habelt, B., Wieske, F., Jackson, M., Khadka, N., Mattei, D., Bernhardt, N., Heinz, A., Liebantz, D., Bikson, M., Padberg, F., Hadar, Ravit, H., Nitsche, M. A., & Winter, C. (2018). Non-invasive modulation reduces repetitive behavior in a rat model through the sensorimotor cortico-striatal circuit. Translational Psychiatry, 8(1). https://doi.org/10.1038/s41398-017-0059-5 PDF
Bikson, M., Paneri, B., Mourdoukoutas, A., Esmaeilpour, Z., Badran, B. W., Azzam, R., Adair, D., Datta, A., Fang, X. H., Wingeier, B., Chao, D., Alonso-Alonso, M., Lee, K., Knotkova, H., Woods, A. J., Hagedorn, D., Jeffery, D., Giordano, J., & Tyler, W. J. (2018). Limited output transcranial electrical stimulation (LOTES-2017): Engineering principles, regulatory statutes, and industry standards for wellness, over-the-counter, or prescription devices with low risk. Brain Stimulation, 11(1), 134-157. https://doi.org/10.1016/j.brs.2017.10.012 PDF
Khadka, N., Zannou, A. L., Zunara, F., Truong, D. Q., Dmochowski, J., & Bikson, M. (2018). Minimal heating at the skin surface during transcranial direct current stimulation. Neuromodulation, 21(4), 334-339. https://doi.org/10.1111/ner.12554 PDF
Charvet, L., Shaw, M., Dobbs, B., Frontario, A., Sherman, K., Bikson, M., Datta, A., Krupp, L., Zeinapour, E., & Kasschau, M. (2018). Remotely Supervised Transcranial Direct Current Stimulation Increases the Benefit of At-Home Cognitive Training in Multiple Sclerosis. Neuromodulation : journal of the International Neuromodulation Society, 21(4), 383–389. https://doi.org/10.1111/ner.12583 PDF
Dmochowski, J. P., Ki, J. J., DeGuzman, P., Sajda, P., & Parra, L. C. (2018). Extracting multidimensional stimulus-response correlations using hybrid encoding-decoding of neural activity. NeuroImage, 180, 134-146. https://doi.org/10.1016/j.neuroimage.2017.05.037 PDF
Charvet, L. E., Dobbs, B., Shaw, M. T., Bikson, M., Datta, A., & Krupp, L. B. (2018). Remotely supervised transcranial direct current stimulation for the treatment of fatigue in multiple sclerosis: Results from a randomized, sham-controlled trial. Multiple Sclerosis Journal, 24(13), 1760-1769. https://doi.org/10.1177/1352458517732842 PDF
Mourdoukoutas, A. P., Truong, D. Q., Adair, D. K., Simon, B. J., & Bikson, M. (2018). High-resolution multi-scale computational model for non-invasive cervical vagus nerve stimulation. Neuromodulation, 21(3), 261-268. https://doi.org/10.1111/ner.12706 PDF
Bikson, M., Brunoni, A. R., Charvet, L. E., Clark, V. P., Cohen, L. G., Deng, Z.-D., Dmochowski, J., Edwards, D. J., Frohlich, F., Kappenman, E. S., Lim, K. O., Loo, C., Mantovani, A., McMullen, D. P., Parra, L. C., Pearson, M., Richardson, J. D., Rumsey, J. M., Sehatpour, P., Sommers, D., Unal, G., Wassermann, E. M., Woods, A. J., & Lisanby, S. H. (2018). Rigor and reproducibility in research with transcranial electrical stimulation: An NIMH-sponsored workshop. Brain Stimulation, 11(3), 465-480. https://doi.org/10.1016/j.brs.2017.12.008 PDF
Leite, J., Gonçalves, Ó. F., Pereira, P., Khadka, N., Bikson, M., Fregni, F., & Carvalho, S. (2018). The differential effects of unihemispheric and bihemispheric tDCS over the inferior frontal gyrus on proactive control. Neuroscience Research, 130, 39-46. https://doi.org/10.1016/j.neures.2017.08.005 PDF
2017
Zareen, N., Shinozaki, M., Ryan, D., Alexander, H., Amer, A., Truong, D. Q., Khadka, N., Sarkar, A., Naeem, S., Bikson, M., & Martin, J. H. (2017). Motor cortex and spinal cord neuromodulation promote corticospinal tract axonal outgrowth and motor recovery after cervical contusion spinal cord injury. Experimental Neurology, 297, 179-189. https://doi.org/10.1016/j.expneurol.2017.08.004 PDF
Esmaeilpour, Z., Marangolo, P., Hampstead, B. M., Bestmann, S., Galletta, E., Knotkova, H., & Bikson, M. (2017). Incomplete evidence that increasing current intensity of tDCS boosts outcomes. Brain Stimulation, 11(2), 310-321. https://doi.org/10.1016/j.brs.2017.12.002 PDF
Meiron, O., Gale, R., Namestnic, J., Bennet-Back, O., David, J., Gebodh, N., Adair, D., Esmaeilpour, & Bikson, M. (2017). High-definition transcranial direct current stimulation in early onset epileptic encephalopathy: A case study. Brain Injury, 32(1), 135-143. https://doi.org/10.1080/02699052.2017.1390254 PDF
dos Santos, M. D., Cavenaghi, V. B., Mac-Kay, A. P. M. G., Serafim, V., Venturi, A., Truong, D. Q., Huang, Y., Boggio, P. S., Fregni, F., Simis, M., Bikson, M., & Gagliardi, R. J. (2017). Non-invasive brain stimulation and computational models in post-stroke aphasic patients: Single session of transcranial magnetic stimulation and transcranial direct current stimulation. A randomized clinical trial. Sao Paulo Medical Journal, 135(5), 475-480. https://doi.org/10.1590/1516-3180.2016.0194060617 PDF
Rawji, V., Ciocca, M., Zacharia, A., Soares, D., Truong, D., Bikson, M., Rothwell, J., & Bestmann, S. (2017). tDCS changes in motor excitability are specific to orientation of current flow. Brain Stimulation, 11(2), 289-298. https://doi.org/10.1016/j.brs.2017.11.001 PDF
Robinson, C., Armenta, M., Combs, A., Lamphere, M. L., Garza, G. J., Neary, J., Wolfe, J. H., Molina, E., Semey, D. E., McKee, C. M., Gallegos, S. J., Jones, A. P., Trumbo, M. C., Al-Azzawi, H., Hunter, M. A., Lieberman, G., Coffman, B. A., Aboseria, M., Bikson, M., Clark, V. P., & Witkiewitz, K. (2017). Modulating affective experience and emotional intelligence with loving kindness meditation and transcranial direct current stimulation: A pilot study. Social Neuroscience, 14(1), 10-25. https://doi.org/10.1080/17470919.2017.1397054 PDF
Bikson, M., Unal, G., Brunoni, A., & Loo, C. (2017). What Psychiatrists Need to Know About Transcranial Direct Current Stimulation. Psychiatric Times. https://www.psychiatrictimes.com/view/what-psychiatrists-need-know-about-transcranial-direct-current-stimulation PDF
Shaw, M. T., Kasschau, M., Dobbs, B., Pawlak, N., Pau, W., Sherman, K., Bikson, M., Datta, A., & Charvet, L. E. (2017). Remotely supervised transcranial direct current stimulation: An update on safety and tolerability. Journal of Visualized Experiments, 2017(128). https://doi.org/10.3791/56211 PDF
Bikson, M., Grossman, P., Zannou, A. L., Kronberg, G., Truong, D., Boggio, P., Brunoni, A. R., Charvet, L., Fregni, F., Fritsch, B., Gillick, B., Hamilton, R. H., Hampstead, B. H., Kirton, A., Knotkova, H., Liebetanz, D., Liu, A., Loo, C., Nitsche, M. A., Reis, J., Richardson, J. D., Rotenberg, A., Turkeltaub, P. E., & Woods, A. J. (2017). Response to letter to the editor: Safety of transcranial direct current stimulation: Evidence based update 2016. Brain Stimulation, 10(5), 986-987. https://doi.org/10.1016/j.brs.2017.06.007 PDF
Jackson, M. P., Bikson, M., Liebetanz, D., & Nitsche, M. (2017). How to consider animal data in tDCS safety standards. Brain Stimulation, 10(6), 1141-1142. https://doi.org/10.1016/j.brs.2017.08.004 PDF
Dmochowski, J. P., Koessler, L., Norcia, A. M., Bikson, M., & Parra, L. C. (2017). Optimal use of EEG recordings to target active brain areas with transcranial electrical stimulation. NeuroImage, 157, 69-80. https://doi.org/10.1016/j.neuroimage.2017.05.059 PDF
Chrysikou, E. G., Berryhill, M. E., Bikson, M., & Coslett, H. B. (2017). Editorial: Revisiting the effectiveness of transcranial direct current brain stimulation for cognition: Evidence, challenges, and open questions. Frontiers in Human Neuroscience, 11. https://doi.org/10.3389/fnhum.2017.00448 PDF
Jackson, M. P., Truong, D., Brownlow, M. L., Wagner, J. A., McKinley, R. A., Bikson, M., & Jankord, R. (2017). Safety parameter considerations of anodal transcranial direct current stimulation in rats. Brain, Behavior, and Immunity, 64, 152-161. https://doi.org/10.1016/j.bbi.2017.04.008 PDF
Boateng, Jr. A., Paneri, B., Dufau, A., Borges, H., Bikson, M. (2017) Proceedings #26: The effect of cooling electrodes on tDCS tolerability. Brain Stimulation, 10(4), e82–e83. https://doi.org/10.1016/j.brs.2017.04.119 PDF
Esmaeilpour, Z., Milosevic, M., Azevedo, K., Khadka, N., Navarro, J., Brunoni, A., Popovic, M. R., Bikson, M., & Fonoff, E. T. (2017) Proceedings #21: Intracranial Voltage Recording During Transcranial Direct Current Stimulation (tDCS) in Human Subjects With Validation of a Standard Model. Brain Stimulation, 10(4), e72–e75. https://doi.org/10.1016/j.brs.2017.04.114 PDF
Shaw, M., Dobbs, B., Pawlak, N., Pau, W., Sherman, K., Bikson, M., Datta, A., Kasschau, M., Frontario A, & Charvet L. (2017). Proceedings #13: Updated Safety and Tolerability of Remotely-Supervised Transcranial Direct Current Stimulation (RS-tDCS). Brain Stimulation, 10(4), e60–e61. https://doi.org/10.1016/j.brs.2017.04.106 PDF
Pawlak, N., Agarwal, S., Biagioni, M., Bikson, M., Datta, A., & Charvet, L. E. (2017). Proceedings #12. Remotely-supervised Transcranial Direct Current Stimulation (RS-tDCS) for Parkinson’s Disease (PD) Clinical Trials: Guidelines and Feasibility. Brain Stimulation, 10(4), e59–e60. https://doi.org/10.1016/j.brs.2017.04.105 PDF
Pau, W., Shaw, M., Dobbs, B., Kasschau, M., Frontario, A., Bikson, M., Datta, A., & Charvet, Leigh. (2017). Proceedings #11. Mood Improvement with Transcranial Direct Current Stimulation (tDCS) is Specific to Positive vs. Negative Affect in Multiple Sclerosis. Brain Stimulation, 10(4), e58-e59. https://doi.org/10.1016/j.brs.2017.04.104 PDF
Dobbs, B., Shaw, M., Frontario, A., Sherman, K., Bikson, M., Datta, A., Kasschau, M., & Charvet, L. (2017). Proceedings #10. Remotely-Supervised Transcranial Direct Current Stimulation (RS-tDCS) Improves Fatigue in Multiple Sclerosis. Brain Stimulation, 10(4), e57-e58. https://doi.org/10.1016/j.brs.2017.04.103 PDF
Rabau, S., Shekhawat, G. S., Aboseria, M., Griepp, D., Van Rompaey, V., Bikson, M., & Van de Heyning, P. (2017). Comparison of the long-term effect of positioning the cathode in tDCS in tinnitus patients. Frontiers in Aging Neuroscience, 9(JUL). https://doi.org/10.3389/fnagi.2017.00217 PDF
Chakraborty, D., Truong, D. Q., Bikson, M., & Kaphzan, H. (2017). Neuromodulation of Axon Terminals. Cerebral cortex (New York, N.Y. : 1991), 28(8), 2786–2794. https://doi.org/10.1093/cercor/bhx158 PDF
Antal, A., Alekseichuk, I., Bikson, M., Brockmöller, J., Brunoni, A. R., Chen, R., Cohen, L. G., Dowthwaite, G., Ellrich, J., Flöel, A., Fregni, F., George, M. S., Hamilton, R., Haueisen, J., Herrmann, C. S., Hummel, F. C., Lefaucheur, J. P., Liebetanz, D., Loo, C. K., McCaig, C. D., Miniussi, C., Miranda, P. C., Moliadze, V., Nitsche, M. A., Nowak, R., Padberg, F., Pascual-Leone, A., Poppendieck, W., Priori, A., Rossi, S., Rossini, P. M., Rothwell, J., Rueger, M. A., Ruffini, G., Schellhorn, K., Siebner, H. R., Ugawa, Y., Wexler, A., Ziemann, U., Hallett, M., & Paulus, W. (2017). Low intensity transcranial electric stimulation: Safety, ethical, legal regulatory and application guidelines. Clinical Neurophysiology, 128(9), 1774-1809. https://doi.org/10.1016/j.clinph.2017.06.001 PDF
Rahman, A., Lafon, B., Parra, L. C., & Bikson, M. (2017). Direct current stimulation boosts synaptic gain and cooperativity in vitro. Journal of Physiology, 595(11), 3535-3547. https://doi.org/10.1113/JP273005 PDF
Dmochowski, J., & Bikson, M. (2017). Noninvasive neuromodulation goes deep. Cell, 169(6), 977-978. https://doi.org/10.1016/j.cell.2017.05.017 PDF
De Paolis, A., Bikson, M., Nelson, J. T., de Ru, J. A., Packer, M., & Cardoso, L. (2017). Analytical and numerical modeling of the hearing system: Advances towards the assessment of hearing damage. Hearing Research, 349, 111-128. https://doi.org/10.1016/j.heares.2017.01.015 PDF
Nitsche, M. A., & Bikson, M. (2017). Extending the parameter range for tDCS: Safety and tolerability of 4 mA stimulation. Brain Stimulation, 10(3), 541-542. https://doi.org/10.1016/j.brs.2017.03.002 PDF
Hampstead, B. M., Sathian, K., Bikson, M., & Stringer, A. Y. (2017). Combined mnemonic strategy training and high-definition transcranial direct current stimulation for memory deficits in mild cognitive impairment. Alzheimer's and Dementia: Translational Research and Clinical Interventions, 3(3), 459-470. https://doi.org/10.1016/j.trci.2017.04.008 PDF
Edwards, D. J., Cortes, M., Wortman-Jutt, S., Putrino, D., Bikson, M., Thickbroom, G., & Pascual-Leone, A. (2017). Transcranial direct current stimulation and sports performance. Frontiers in Human Neuroscience, 11. https://doi.org/10.3389/fnhum.2017.00243 PDF
Ezquerro, F., Moffa, A. H., Bikson, M., Khadka, N., Aparicio, L. V. M., de Sampaio-Junior, B., Fregni, F., Bensenor, I. M., Lotufo, P. A., Pereira, A. C., & Brunoni, A. R. (2017). The influence of skin redness on blinding in transcranial direct current stimulation studies: A crossover trial. Neuromodulation, 20(3), 248-255. https://doi.org/10.1111/ner.12527 PDF
Chen, C. -., Bikson, M., Chou, L. -., Shan, C., Khadka, N., Chen, W. -., & Fregni, F. (2017). Higher-order power harmonics of pulsed electrical stimulation modulates corticospinal contribution of peripheral nerve stimulation. Scientific Reports, 7. https://doi.org/10.1038/srep43619 PDF
Cancelli, A., Cottone, C., Tecchio, F., Truong, D., Dmochowski, J., Adair, D., & Bikson, M. (2017) P094 Method for EEG guided transcranial Electrical Stimulation without models. Clinical Neurophysiology, 128(3), e54–e56. https://doi.org/10.1016/j.clinph.2016.10.219 PDF
Gebodh, N., Adair, D., Chelette, K., Esmaeilpour, Z., Bikson, M., Dmochowski, J., Parra, L. C., Woods, A., & Kappenman, E. (2017). Modulation of physiologic artifacts during concurrent tDCS and EEG. Brain Stimulation, 10, 429-430. https://doi.org/10.1016/j.brs.2017.01.278 PDF
Gebodh, N., Adair, D., Chelette, K., Esmaeilpour, Z., Bikson, M., Dmochowski, J., Woods, A. & Kappenman, E. (2017). Physiologic Artifacts When Combining EEG and tDCS. Brain Stimulation, 10(33). https://doi.org/10.1016/j.brs.2017.04.051 PDF
Bai, S., Gálvez, V., Dokos, S., Martin, D., Bikson, M., & Loo, C. (2017). Computational models of bitemporal, bifrontal and right unilateral ECT predict differential stimulation of brain regions associated with efficacy and cognitive side effects. European Psychiatry, 41, 21-29. https://doi.org/10.1016/j.eurpsy.2016.09.005 PDF
Esmaeilpour, Z., Schestatsky, P., Bikson, M., Brunoni, A. R., Pellegrinelli, A., Piovesan, F. X., Santos, M. M. S. A., Menezes, R. B., & Fregni, F. (2017). Notes on human trials of transcranial direct current stimulation between 1960 and 1998. Frontiers in Human Neuroscience, 11 https://doi.org/10.3389/fnhum.2017.00071 PDF
Giordano, J., Bikson, M., Kappenman, E. S., Clark, V. P., Coslett, H. B., Hamblin, M. R., Hamilton, R., Jankord, R., Kozumbo, W. J., McKinley, R. A., Nitsche, M. A., Reilly, J. P., Richardson, J., Wurzman, R., & Calabrese, E. (2017). Mechanisms and effects of transcranial direct current stimulation. Dose-Response, 15(1). https://doi.org/10.1177/1559325816685467 PDF
Huang, Y., Liu, A. A., Lafon, B., Friedman, D., Dayan, M., Wang, X., Bikson, M., Doyle, W. K., Devinsky, O., & Parra, L. C. (2017). Measurements and models of electric fields in the in vivo human brain during transcranial electric stimulation. eLife, 6. https://doi.org/10.7554/eLife.18834 (*authors contributed equally). PDF Summary video
Kronberg, G., Bridi, M., Abel, T., Bikson, M., & Parra, L. C. (2017). Direct current stimulation modulates LTP and LTD: Activity dependence and dendritic effects. Brain Stimulation, 10(1), 51-58. https://doi.org/10.1016/j.brs.2016.10.001 PDF
Lafon, B., Rahman, A., Bikson, M., & Parra, L. C. (2017). Direct current stimulation alters neuronal Input/Output function. Brain Stimulation, 10(1), 36-45. https://doi.org/10.1016/j.brs.2016.08.014 PDF
Sebastian, R., Saxena, S., Tsapkini, K., Faria, A. V., Long, C., Wright, A., Davis, C., Tippett, D. C., Mourdoukoutas, A. P., Bikson, M., Celnik, P., & Hillis, A. E. (2017). Cerebellar tDCS: A novel approach to augment language treatment post-stroke. Frontiers in Human Neuroscience, 10. https://doi.org/10.3389/fnhum.2016.00695 PDF
De Paolis, A., Watanabe, H., Nelson, J. T., Bikson, M., Packer, M., & Cardoso, L. (2017). Human cochlear hydrodynamics: A high-resolution μCT-based finite element study. Journal of Biomechanics, 50, 209-216. https://doi.org/10.1016/j.jbiomech.2016.11.020 PDF
2016
Shin, D. W., Khadka, N., Fan, J., Bikson, M., & Fu, B. M. (2016). Transcranial direct current stimulation transiently increases the blood-brain barrier solute permeability in vivo. Paper presented at the Progress in Biomedical Optics and Imaging - Proceedings of SPIE, 9788. https://doi.org/10.1117/12.2218197 PDF
Kasschau, M., Reisner, J., Sherman, K., Bikson, M., Datta, A., & Charvet, L. E. (2016). Transcranial direct current stimulation is feasible for remotely supervised home delivery in multiple sclerosis. Neuromodulation, 19(8), 824-831. https://doi.org/10.1111/ner.12430 PDF
Jackson, M. P., Rahman, A., Lafon, B., Kronberg, G., Ling, D., Parra, L. C., & Bikson, M. (2016). Animal models of transcranial direct current stimulation: Methods and mechanisms. Clinical Neurophysiology, 127(11), 3425-3454. https://doi.org/10.1016/j.clinph.2016.08.016 PDF
Alonzo, A., Aaronson, S., Bikson, M., Husain, M., Lisanby, S., Martin, D., McClintock, S. M., McDonald, W. M., O’Reardon, J., Esmaeilpour, Z., & Loo, C. (2016). Study design and methodology for a multicentre, randomised controlled trial of transcranial direct current stimulation as a treatment for unipolar and bipolar depression. Contemporary Clinical Trials, 51, 65-71. https://doi.org/10.1016/j.cct.2016.10.002 PDF
Teichmann, M., Lesoil, C., Godard, J., Vernet, M., Bertrand, A., Levy, R., Dubois, B., Lemoine, L., Truong, D. Q., Bikson, M., Kas, A., & Valero-Cabré, A. (2016). Direct current stimulation over the anterior temporal areas boosts semantic processing in primary progressive aphasia. Annals of Neurology, 80(5), 693-707. https://doi.org/10.1002/ana.24766 PDF
Jog, M. V., Smith, R. X., Jann, K., Dunn, W., Lafon, B., Truong, D., Wu, A., Parra, L. C., Bikson, M., & Wang, D. J. J. (2016). In-vivo imaging of magnetic fields induced by transcranial direct current stimulation (tDCS) in human brain using MRI. Scientific Reports, 6. https://doi.org/10.1038/srep34385 PDF
Paneri, B., Adair, D., Thomas, C., Khadka, N., Patel, V., Tyler, W. J., Parra, L.C., & Bikson, M. (2016). Tolerability of repeated application of transcranial electrical stimulation with limited outputs to healthy subjects. Brain Stimulation, 9(5), 740-754. https://doi.org/10.1016/j.brs.2016.05.008 PDF
Babyar, S., Santos-Pontelli, T., Will-Lemos, T., Mazin, S., Bikson, M., Truong, D. Q., Edwards, D., & Reding, M. (2016). Center of pressure speed changes with tDCS versus GVS in patients with lateropulsion after stroke. Brain Stimulation, 9(5), 796-798. https://doi.org/10.1016/j.brs.2016.06.053 PDF
Bikson, M., Grossman, P., Thomas, C., Zannou, A. L., Jiang, J., Adnan, T., Mourdoukoutas, A. P., Kronberg, G., Truong, D. Q., Boggio, P., Brunoni, A. R., Charvet, L., Fregni, F., Fritsch, B., Gillick, B., Hamilton, R. H., Hampstead, B. M., Jankord, R., Kirton, A., Knotkova, H., Liebetanz, D., Liu, A., Loo, C., Nitsche, M. A., Reis, J., Richardson, J. D., Rotenberg, A., Turkeltaub, P. E., & Woods, A. J. (2016). Safety of transcranial direct current stimulation: Evidence based update 2016. Brain Stimulation, 9(5), 641-661. https://doi.org/10.1016/j.brs.2016.06.004 PDF
Hogeveen, J., Grafman, J., Aboseria, M., David, A., Bikson, M., & Hauner, K. K. (2016). Effects of high-definition and conventional tDCS on response inhibition. Brain Stimulation, 9(5), 720-729. https://doi.org/10.1016/j.brs.2016.04.015 PDF
Dmochowski, J., Koessler, L., Parra, L., Bikson, M., & Norcia, A. (2016). Targeted electrical stimulation of active brain sources using reciprocity. https://doi.org/10.1101/078758 PDF
Bikson, M., Paneri, B., & Giordano, J. (2016). The off-label use, utility and potential value of tDCS in the clinical care of particular neuropsychiatric conditions. Journal of law and the biosciences, 3(3), 642–646. https://doi.org/10.1093/jlb/lsw044 PDF
Cappiello, M., Xie, W., David, A., Bikson, M., & Zhang, W. (2016). Transcranial direct current stimulation modulates pattern separation. Neuroreport, 27(11), 826-832. https://doi.org/10.1097/WNR.0000000000000621 PDF
Alam, M., Truong, D. Q., Khadka, N., & Bikson, M. (2016). Spatial and polarity precision of concentric high-definition transcranial direct current stimulation (HD-tDCS). Physics in Medicine and Biology, 61(12), 4506-4521. https://doi.org/10.1088/0031-9155/61/12/4506 PDF
Cancelli, A., Cottone, C., Tecchio, F., Truong, D. Q., Dmochowski, J., & Bikson, M. (2016). A simple method for EEG guided transcranial electrical stimulation without models. Journal of Neural Engineering, 13(3). https://doi.org/10.1088/1741-2560/13/3/036022 PDF
Hampstead, B. M., Briceño, E. M., Mascaro, N., Mourdoukoutas, A., & Bikson, M. (2016). Current status of transcranial direct current stimulation in posttraumatic stress and other anxiety disorders. Current Behavioral Neuroscience Reports, 3(2), 95-101. https://doi.org/10.1007/s40473-016-0070-9 PDF
Dias, D. R., Trevizol, A. P., Miorin, L. A., Bikson, M., Aboseria, M., Shiozawa, P., & Cordeiro, Q. (2016). Effect of transcranial direct current stimulation protocol for treating depression among hemodialysis patients. Journal of ECT, 32(2), e3-e4. https://doi.org/10.1097/YCT.0000000000000273 PDF
Hämmerer, D., Bonaiuto, J., Klein-Flügge, M., Bikson, M., & Bestmann, S. (2016). Selective alteration of human value decisions with medial frontal tDCS is predicted by changes in attractor dynamics. Scientific Reports, 6. https://doi.org/10.1038/srep25160 PDF
Santos-Pontelli, T. E. G., Rimoli, B. P., Favoretto, D. B., Mazin, S. C., Truong, D. Q., Leite, J. P., Pontes-Neto, O. M., Babyar, S. R., Reding, M., Bikson, M., & Edwards, D. J. (2016). Polarity-dependent misperception of subjective visual vertical during and after transcranial direct current stimulation (tDCS). PLoS ONE, 11(3). https://doi.org/10.1371/journal.pone.0152331 PDF
Woods, A. J., Antal, A., Bikson, M., Boggio, P. S., Brunoni, A. R., Celnik, P., Cohen, L. G., Fregni, F., Herrmann, C. S., Kappenman, E. S., Knotkova, H., Liebetanz, D., Miniussi, C., Miranda, P. C., Paulus, W., Priori, A., Reato, D., Stagg, C., Wenderoth, N., & Nitsche, M. A. (2016). A technical guide to tDCS, and related non-invasive brain stimulation tools. Clinical Neurophysiology, 127(2), 1031-1048. https://doi.org/10.1016/j.clinph.2015.11.012 PDF
Castillo-Saavedra, L., Gebodh, N., Bikson, M., Diaz-Cruz, C., Brandao, R., Coutinho, L., Truong, D. Q., Datta, A., Shani-Hershkovich, R., Weiss, M., Laufer, I., Reches, A., Pereman, Z., Geva, A., Parra, L. C., & Fregni, F. (2016). Clinically effective treatment of fibromyalgia pain with high-definition transcranial direct current stimulation: Phase II open-label dose optimization. Journal of Pain, 17(1), 14-26. https://doi.org/10.1016/j.jpain.2015.09.009 PDF
2015
Sarantos, C., Bekritsky, J., Khadka, N., Bikson, M., & Adusumilli, P. (2015). Design of wireless intra-operative pulse oximeter with reticulated pressure-sensitive head. Journal of Medical Devices, Transactions of the ASME, 9(3). https://doi.org/10.1115/1.4030600 PDF
Rahman, A., Lafon, B., & Bikson, M. (2015). Multilevel computational models for predicting the cellular effects of noninvasive brain stimulation. Progress in brain research, 222, 25–40. https://doi.org/10.1016/bs.pbr.2015.09.003 PDF
Bikson, M., Truong, D. Q., Mourdoukoutas, A. P., Aboseria, M., Khadka, N., Adair, D., & Rahman, A. (2015). Modeling sequence and quasi-uniform assumption in computational neurostimulation. Progress in brain research, 222, 1–23. https://doi.org/10.1016/bs.pbr.2015.08.005 PDF
Cancelli, A., Cottone, C., Parazzini, M., Fiocchi, S., Truong, D., Bikson, M., & Tecchio, F. (2015). Transcranial direct current stimulation: Personalizing the neuromodulation. Paper presented at the Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS, , 2015-November 234-237. https://doi.org/10.1109/EMBC.2015.7318343 PDF
Knotkova, H., Woods, A. J., Bikson, M., & Nitsche, M. A. (2015). Transcranial Direct Current Stimulation (tDCS): What Pain Practitioners Need to Know. Retrieved October 20, 2020, from Practical Pain Management website: https://www.practicalpainmanagement.com/treatments/interventional/stimulators/transcranial-direct-current-stimulation-tdcs-what-pain link
Kasschau, M., Sherman, K., Haider, L., Frontario, A., Shaw, M., Datta, A., Bikson, M., & Charvet, L. (2015). A protocol for the use of remotely-supervised transcranial direct current stimulation (tDCS) in multiple sclerosis (MS). Journal of Visualized Experiments, 2015(106). https://doi.org/10.3791/53542 Video PDF
Donnell, A., Nascimento, T. D., Lawrence, M., Gupta, V., Zieba, T., Truong, D. Q., Bikson, M., Datta, A., Bellile, E., & DaSilva, A. F. (2015). High-definition and non-invasive brain modulation of pain and motor dysfunction in chronic TMD. Brain Stimulation, 8(6), 1085-1092. https://doi.org/10.1016/j.brs.2015.06.008 PDF
Galletta, E. E., Cancelli, A., Cottone, C., Simonelli, I., Tecchio, F., Bikson, M., & Marangolo, P. (2015). Use of computational modeling to inform tDCS electrode montages for the promotion of language recovery in post-stroke aphasia. Brain Stimulation, 8(6), 1108-1115. https://doi.org/10.1016/j.brs.2015.06.018 PDF
Xu, J., Healy, S. M., Truong, D. Q., Datta, A., Bikson, M., & Potenza, M. N. (2015). A feasibility study of bilateral anodal stimulation of the prefrontal cortex using high-definition electrodes in healthy participants. Yale Journal of Biology and Medicine, 88(3), 219-225. PDF
Kurimori, M., Shiozawa, P., Bikson, M., Aboseria, M., & Cordeiro, Q. (2015). Targeting negative symptoms in schizophrenia: Results from a proof-of-concept trial assessing prefrontal anodic tDCS protocol. Schizophrenia Research, 166(1-3), 362-363. https://doi.org/10.1016/j.schres.2015.05.029 PDF
DaSilva, A. F., Truong, D. Q., DosSantos, M. F., Toback, R. L., Datta, A., & Bikson, M. (2015). State-of-art neuroanatomical target analysis of high-definition and conventional tDCS montages used for migraine and pain control. Frontiers in Neuroanatomy, 9(July). https://doi.org/10.3389/fnana.2015.00089 PDF
Senço, N. M., Huang, Y., D'Urso, G., Parra, L. C., Bikson, M., Mantovani, A., Shavitt, r. G., Hoexter, M. Q., Miguel, E. C., & Brunoni, A. R. (2015). Transcranial direct current stimulation in obsessive-compulsive disorder: Emerging clinical evidence and considerations for optimal montage of electrodes. Expert Review of Medical Devices, 12(4), 381-391. https://doi.org/10.1586/17434440.2015.1037832 PDF
Nitsche, M. A., Bikson, M., & Bestmann, S. (2015). On the use of meta-analysis in neuromodulatory non-invasive brain stimulation. Brain Stimulation, 8(3), 666-667. https://doi.org/10.1016/j.brs.2015.03.008 PDF
Seibt, O., Brunoni, A. R., Huang, Y., & Bikson, M. (2015). The pursuit of DLPFC: Non-neuronavigated methods to target the left dorsolateral pre-frontal cortex with symmetric bicephalic transcranial direct current stimulation (tDCS). Brain Stimulation, 8(3), 590-602. https://doi.org/10.1016/j.brs.2015.01.401 PDF
Brunoni, A. R., Sampaio, B., Moffa, A. H., Borrione, L., Nogueira, B. S., Aparício, L. V. M., Veronezi, B., Moreno, M., Fernandes, R. A., Tavares, D., Bueno, P. V., S., Seibt, O., Bikson, M., Fraguas, R., & Benseñor, I. E. M. (2015). The escitalopram versus electric current therapy for treating depression clinical study (ELECT-TDCS): Rationale and study design of a non-inferiority, triple-arm, placebo-controlled clinical trial. [Estudo clinico Escitalopram versus Eletroterapia no Tratamento da Depressao (ELECT-TDCS): Racional e desenho de estudo de um ensaio de nao inferioridade, de tres bracos, placebo-controlado] Sao Paulo Medical Journal, 133(3), 252-263. https://doi.org/10.1590/1516-3180.2014.00351712 PDF
Shekhawat, G. S., Sundram, F., Bikson, M., Truong, D., De Ridder, D., Stinear, C. M., Welch, D., & Searchfield, G. D. (2015). Intensity, duration, and location of high-definition transcranial direct current stimulation for tinnitus relief. Neurorehabilitation and Neural Repair, 30(4), 349-359. https://doi.org/10.1177/1545968315595286 PDF
Khadka, N., Truong, D. Q., & Bikson, M. (2015). Principles of within electrode current steering. Journal of Medical Devices, Transactions of the ASME, 9(2), 1-2. https://doi.org/10.1115/1.4030126 PDF
Jones, K. T., Stephens, J. A., Alam, M., Bikson, M., & Berryhill, M. E. (2015). Longitudinal neurostimulation in older adults improves working memory. PLoS ONE, 10(4). https://doi.org/10.1371/journal.pone.0121904 PDF
Song, W., Truong, D. Q., Bikson, M., & Martin, J. H. (2015). Transspinal direct current stimulation immediately modifies motor cortex sensorimotor maps. Journal of Neurophysiology, 113(7), 2801-2811. https://doi.org/10.1152/jn.00784.2014 PDF
Grecco, L., Li, S., Michel, S., Castillo-Saavedra, L., Mourdoukoutas, A., Bikson, M., & Fregni, F. (2015) Transcutaneous spinal stimulation as a therapeutic strategy for spinal cord injury: state of the art. Journal of Neurorestoratology, 3(MAR), 73-82. https://doi.org/10.2147/JN.S77813 PDF
Charvet, L. E., Kasschau, M., Datta, A., Knotkova, H., Stevens, M. C., Alonzo, A., & Bikson, M. (2015). Remotely-supervised transcranial direct current stimulation (tDCS) for clinical trials: Guidelines for technology and protocols. Frontiers in Systems Neuroscience, 9(MAR). https://doi.org/10.3389/fnsys.2015.00026 PDF
Fregni, F., Nitsche, M. A., Loo, C. K., Brunoni, A. R., Marangolo, P., Leite, J., Carvalho, S., Bolognini N., Caumo, W., Paik, N. J., Simis, M., Ueda, K., Ekhtiari, H., Luu, P., Tucker, D. M., Tyler, w. J., Brunelin, J., Datta, A., Juan, C. H., Venkatasubramanian, G. Boggio, P. S., & Bikson, M. (2015). Regulatory considerations for the clinical and research use of transcranial direct current stimulation (tDCS): Review and recommendations from an expert panel. Clinical Research and Regulatory Affairs, 32(1), 22-35. https://doi.org/10.3109/10601333.2015.980944 PDF
Reato, D., Bikson, M., & Parra, L. C. (2015). Lasting modulation of in vitro oscillatory activity with weak direct current stimulation. Journal of Neurophysiology, 113(5), 1334-1341. https://doi.org/10.1152/jn.00208.2014 PDF
Foerster, B. R., Nascimento, T. D., DeBoer, M., Bender, M. A., Rice, I. C., Truong, D. Q., Bikson, M., Clauw, D. J., Zubieta, J.-K., Harris, R. E., & DaSilva, A. F. (2015). Brief report: Excitatory and inhibitory brain metabolites as targets of motor cortex transcranial direct current stimulation therapy and predictors of its efficacy in fibromyalgia. Arthritis and Rheumatology, 67(2), 576-581. https://doi.org/10.1002/art.38945 PDF
Khadka, N., Rahman, A., Sarantos, C., Truong, D. Q., & Bikson, M. (2015). Methods for specific electrode resistance measurement during transcranial direct current stimulation. Brain Stimulation, 8(1), 150-159. https://doi.org/10.1016/j.brs.2014.10.004 PDF
2014
Bikson, M., Edwards, D., & Kappenman, E. (2014). The outlook for non-invasive electrical brain stimulation. Brain Stimulation, 7(6), 771-772. https://doi.org/10.1016/j.brs.2014.10.005 PDF
Toshev, P. K., Guleyupoglu, B., & Bikson, M. (2014). Informing dose design by modeling transcutaneous spinal direct current stimulation. Clinical Neurophysiology, 125(11), 2147-2149. https://doi.org/10.1016/j.clinph.2014.03.022 PDF
Gillick, B. T., Kirton, A., Carmel, J. B., Minhas, P., & Bikson, M. (2014). Pediatric stroke and transcranial direct current stimulation: Methods for rational individualized dose optimization. Frontiers in Human Neuroscience, 8. https://doi.org/10.3389/fnhum.2014.00739 PDF
Scheldrup, M., Greenwood, P. M., McKendrick, R., Strohl, J., Bikson, M., Alam, M., McKinley, R. A., & Parasuraman, R. (2014). Transcranial direct current stimulation facilitates cognitive multi-task performance differentially depending on anode location and subtask. Frontiers in Human Neuroscience, 8(SEP). https://doi.org/10.3389/fnhum.2014.00665 PDF
DosSantos, M. F., Martikainen, I. K., Nascimento, T. D., Love, T. M., DeBoer, M. D., Schambra, H. M., Bikson, M., Zubieta, J.-K., & DaSilva, A. F. (2014). Building up analgesia in humans via the endogenous μ-opioid system by combining placebo and active tDCS: A preliminary report. PLoS ONE, 9(7). https://doi.org/10.1371/journal.pone.0102350 PDF
Richardson, J. D., Fillmore, P., Datta, A., Truong, D., Bikson, M., & Fridriksson, J. (2014). Toward development of sham protocols for high-definition transcranial direct current stimulation (HD-tDCS). NeuroRegulation, 1(1), 62-72. https://doi.org/10.15540/nr.1.1.62 PDF
Guleyupoglu, B., Febles, N., Minhas, P., Hahn, C., & Bikson, M. (2014). Reduced discomfort during high-definition transcutaneous stimulation using 6% benzocaine. Frontiers in Neuroengineering, 7(JUL). https://doi.org/10.3389/fneng.2014.00028 PDF
Guarienti, F., Caumo, W., Shiozawa, P., Cordeiro, Q., Boggio, P. S., Benseñor, I. M., Lotufo, P. A., Bikson, M., & Brunoni, A. R. (2014). Reducing transcranial direct current stimulation-induced erythema with skin pretreatment: Considerations for sham-controlled clinical trials. Neuromodulation, 18(4), 261-265. https://doi.org/10.1111/ner.12230 PDF
Moreno-Duarte, I., Gebodh, N., Schestatsky, P., Guleyupoglu, B., Reato, D., Bikson, M., & Fregni, F. (2014). Transcranial electrical stimulation: Transcranial direct current stimulation (tDCS), transcranial alternating current stimulation (tACS), transcranial pulsed current stimulation (tPCS), and transcranial random noise stimulation (tRNS). The stimulated brain: Cognitive enhancement using non-invasive brain stimulation, 35-59. https://doi.org/10.1016/B978-0-12-404704-4.00002-8 PDF
Truong, D., Minhas, P., Nair, A., & Bikson, M. (2014). Computational modeling assisted design of optimized and individualized transcranial direct current stimulation protocols. The stimulated brain: Cognitive enhancement using non-invasive brain stimulation, 85-115. https://doi.org/10.1016/B978-0-12-404704-4.00004-1 PDF
Antal, A., Bikson, M., Datta, A., Lafon, B., Dechent, P., Parra, L. C., & Paulus, W. (2014). Imaging artifacts induced by electrical stimulation during conventional fMRI of the brain. NeuroImage, 85, 1040-1047. https://doi.org/10.1016/j.neuroimage.2012.10.026 (Cover). PDF
Woods, A. J., Hamilton, R. H., Kranjec, A., Minhaus, P., Bikson, M., Yu, J., & Chatterjee, A. (2014). Space, time, and causality in the human brain. NeuroImage, 92, 285-297. https://doi.org/10.1016/j.neuroimage.2014.02.015 PDF
Truong, D. Q., Hüber, M., Xie, X., Datta, A., Rahman, A., Parra, L. C., Dmochowski, J., & Bikson, M. (2014). Clinician accessible tools for GUI computational models of transcranial electrical stimulation: BONSAI and SPHERES. Brain Stimulation, 7(4), 521-524. https://doi.org/10.1016/j.brs.2014.03.009 PDF Use the free modeling tools here: BONSAI and SPHERES
Schambra, H. M., Bikson, M., Wager, T. D., Dossantos, M. F., & Dasilva, A. F. (2014). It's all in your head: Reinforcing the placebo response with tDCS. Brain Stimulation, 7(4), 623-624. https://doi.org/10.1016/j.brs.2014.04.002 Letter-to-Editor. PDF
Brunoni, A. R., Shiozawa, P., Truong, D., Javitt, D. C., Elkis, H., Fregni, F., & Bikson, M. (2014). Understanding tDCS effects in schizophrenia: A systematic review of clinical data and an integrated computation modeling analysis. Expert Review of Medical Devices, 11(4), 383-394. https://doi.org/10.1586/17434440.2014.911082 PDF
Shahid, S. S., Bikson, M., Salman, H., Wen, P., & Ahfock, T. (2014). The value and cost of complexity in predictive modelling: Role of tissue anisotropic conductivity and fibre tracts in neuromodulation. Journal of Neural Engineering, 11(3) https://doi.org/10.1088/1741-2560/11/3/036002 PDF
Manuel, A. L., David, A. W., Bikson, M., & Schnider, A. (2014). Frontal tDCS modulates orbitofrontal reality filtering. Neuroscience, 265, 21-27. https://doi.org/10.1016/j.neuroscience.2014.01.052 PDF
Weiss, S. A., & Bikson, M. (2014). Open questions on the mechanisms of neuromodulation with applied and endogenous electric fields. Frontiers in Human Neuroscience, 8(1 APR). https://doi.org/10.3389/fnhum.2014.00227 PDF Opening editorial to special issue co-edited by M. Bikson and S.H Weiss
Rahman, A., Toshev, P. K., & Bikson, M. (2014). Polarizing cerebellar neurons with transcranial direct current stimulation. Clinical Neurophysiology, 125(3), 435-438. https://doi.org/10.1016/j.clinph.2013.10.003 PDF
Woods, A. J., Hamilton, R. H., Kranjec, A., Minhaus, P., Bikson, M., Yu, J. & Chatterjee, A. (2014). Exploring structure-function relationships using parallel fMRI and tDCS. Brain Stimulation, 7(9). https://doi.org/10.1016/j.brs.2014.01.033 PDF
2013
Kessler, S. K., Minhas, P., Woods, A. J., Rosen, A., Gorman, C., & Bikson, M. (2013). Dosage considerations for transcranial direct current stimulation in children: A computational modeling study. PLoS ONE, 8(9). https://doi.org/10.1371/journal.pone.0076112 PDF
Bikson, M., Bestmann, S., & Edwards, D. (2013). Transcranial devices are not playthings. Nature, 501(7466), 167. https://doi.org/10.1038/501167b PDF
Guleyupoglu, B., Schestatsky, P., Edwards, D., Fregni, F., & Bikson, M. (2013). Classification of methods in transcranial electrical stimulation (tES) and evolving strategy from historical approaches to contemporary innovations. Journal of Neuroscience Methods, 219(2), 297-311. https://doi.org/10.1016/j.jneumeth.2013.07.016 PDF Journal Link
de Berker, A. O., Bikson, M., & Bestmann, S. (2013). Predicting the behavioral impact of transcranial direct current stimulation: Issues and limitations. Frontiers in Human Neuroscience, (OCT). https://doi.org/10.3389/fnhum.2013.00613 PDF
Bikson, M., & Rahman, A. (2013). Origins of specificity during tDCS: Anatomical, activity-selective, and input-bias mechanisms. Frontiers in Human Neuroscience, (OCT). https://doi.org/10.3389/fnhum.2013.00688 PDF
Reato, D., Rahman, A., Bikson, M., & Parra, L. C. (2013). Effects of weak transcranial alternating current stimulation on brain activity-a review of known mechanisms from animal studies. Frontiers in Human Neuroscience, (OCT). https://doi.org/10.3389/fnhum.2013.00687 Journal Link PDF
Bikson, M., Dmochowski, J., & Rahman, A. (2013). The "quasi-uniform" assumption in animal and computational models of non-invasive electrical stimulation. Brain Stimulation, 6(4), 704-705. https://doi.org/10.1016/j.brs.2012.11.005 PDF
Datta, A., Zhou, X., Su, Y., Parra, L. C., & Bikson, M. (2013). Validation of finite element model of transcranial electrical stimulation using scalp potentials: Implications for clinical dose. Journal of Neural Engineering, 10(3). https://doi.org/10.1088/1741-2560/10/3/036018 PDF
Dmochowski, J. P., Datta, A., Huang, Y., Richardson, J. D., Bikson, M., Fridriksson, J., & Parra, L. C. (2013). Targeted transcranial direct current stimulation for rehabilitation after stroke. NeuroImage, 75, 12-19. https://doi.org/10.1016/j.neuroimage.2013.02.049 PDF
Moreno-Duarte, I., Morse, L. R., Alam, M., Bikson, M., Zafonte, R., & Fregni, F. (2013). Targeted therapies using electrical and magnetic neural stimulation for the treatment of chronic pain in spinal cord injury. NeuroImage, 85, 1003-1013. https://doi.org/10.1016/j.neuroimage.2013.05.097 PDF
Okano, A. H., Fontes, E. B., Montenegro, R. A., De Tarso Veras Farinatti, P., Cyrino, E. S., Li, L. M., Bikson, M., & Noakes, T. D. (2013). Brain stimulation modulates the autonomic nervous system, rating of perceived exertion and performance during maximal exercise. British Journal of Sports Medicine, 49(18), 1213-1218. https://doi.org/10.1136/bjsports-2012-091658 PDF
Cano, T., Morales-Quezada, J. L., Bikson, M., & Fregni, F. (2013). Methods to focalize noninvasive electrical brain stimulation: Principles and future clinical development for the treatment of pain. Expert Review of Neurotherapeutics, 13(5), 465-467. https://doi.org/10.1586/ern.13.41 PDF
Rahman, A., Reato, D., Arlotti, M., Gasca, F., Datta, A., Parra, L. C., & Bikson, M. (2013). Cellular effects of acute direct current stimulation: Somatic and synaptic terminal effects. Journal of Physiology, 591(10), 2563-2578. https://doi.org/10.1113/jphysiol.2012.247171 PDF
Truong, D. Q., Magerowski, G., Blackburn, G. L., Bikson, M., & Alonso-Alonso, M. (2013). Computational modeling of transcranial direct current stimulation (tDCS) in obesity: Impact of head fat and dose guidelines. NeuroImage: Clinical, 2(1), 759-766. https://doi.org/10.1016/j.nicl.2013.05.011 PDF
Edwards, D., Cortes, M., Datta, A., Minhas, P., Wassermann, E. M., & Bikson, M. (2013). Physiological and modeling evidence for focal transcranial electrical brain stimulation in humans: A basis for high-definition tDCS. NeuroImage, 74, 266-275. https://doi.org/10.1016/j.neuroimage.2013.01.042 PDF
Villamar, M. F., Volz, M. S., Bikson, M., Datta, A., Dasilva, A. F., & Fregni, F. (2013). Technique and considerations in the use of 4x1 ring high-definition transcranial direct current stimulation (HD-tDCS). Journal of Visualized Experiments : JoVE, (77). https://doi.org/10.3791/50309 PDF WATCH
Chrysikou, E. G., Hamilton, R. H., Coslett, H. B., Datta, A., Bikson, M., & Thompson-Schill, S. L. (2013). Noninvasive transcranial direct current stimulation over the left prefrontal cortex facilitates cognitive flexibility in tool use. Cognitive Neuroscience, 4(2), 81-89. https://doi.org/10.1080/17588928.2013.768221 PDF TEXT
Villamar, M. F., Wivatvongvana, P., Patumanond, J., Bikson, M., Truong, D. Q., Datta, A., & Fregni, F. (2013). Focal modulation of the primary motor cortex in fibromyalgia using 4×1-ring high-definition transcranial direct current stimulation (HD-tDCS): Immediate and delayed analgesic effects of cathodal and anodal stimulation. Journal of Pain, 14(4), 371-383. https://doi.org/10.1016/j.jpain.2012.12.007 PDF
Reato, D., Gasca, F., Datta, A., Bikson, M., Marshall, L., & Parra, L. C. (2013). Transcranial electrical stimulation accelerates human sleep homeostasis. PLoS Computational Biology, 9(2). https://doi.org/10.1371/journal.pcbi.1002898 PDF LINK
Hahn, C., Rice, J., Macuff, S., Minhas, P., Rahman, A., & Bikson, M. (2013). Methods for extra-low voltage transcranial direct current stimulation: Current and time dependent impedance decreases. Clinical Neurophysiology, 124(3), 551-556. https://doi.org/10.1016/j.clinph.2012.07.028 PDF
Datta, A., Dmochowski, J. P., Guleyupoglu, B., Bikson, M., & Fregni, F. (2013). Cranial electrotherapy stimulation and transcranial pulsed current stimulation: A computer based high-resolution modeling study. NeuroImage, 65, 280-287. https://doi.org/10.1016/j.neuroimage.2012.09.062 PDF
Kuo, H. -., Bikson, M., Datta, A., Minhas, P., Paulus, W., Kuo, M. -., & Nitsche, M. A. (2013). Comparing cortical plasticity induced by conventional and high-definition 4 × 1 ring tDCS: A neurophysiological study. Brain Stimulation, 6(4), 644-648. doi:10.1016/j.brs.2012.09.010 PDF Journal Link
Weiss, S. A., McKhann Jr., G., Goodman, R., Emerson, R. G., Trevelyan, A., Bikson, M., & Schevon, C. A. (2013). Field effects and ictal synchronization: Insights from in homine observations. Frontiers in Human Neuroscience, 7(DEC). https://doi.org/10.3389/fnhum.2013.00828 PDF
2012
Datta, A., Truong, D., Minhas, P., Parra, L. C., & Bikson, M. (2012). Inter-individual variation during transcranial direct current stimulation and normalization of dose using MRI-derived computational models. Frontiers in Psychiatry, 3(OCT). https://doi.org/10.3389/fpsyt.2012.00091 PDF
Bikson, M., Rahman, A., & Datta, A. (2012). Computational models of transcranial direct current stimulation. Clinical EEG and Neuroscience, 43(3), 176-183. https://doi.org/10.1177/1550059412445138 PDF
Dasilva, A. F., Mendonca, M. E., Zaghi, S., Lopes, M., Dossantos, M. F., Spierings, E. L., Bajwa, Z., Datta, A., Bikson, M., & Fregni, F. (2012). TDCS-induced analgesia and electrical fields in pain-related neural networks in chronic migraine. Headache, 52(8), 1283-1295. https://doi.org/10.1111/j.1526-4610.2012.02141.x PDF
Medina, J., Beauvais, J., Datta, A., Bikson, M., Coslett, H. B., & Hamilton, R. H. (2012). Transcranial direct current stimulation accelerates allocentric target detection. Brain Stimulation, 6(3), 433-439. https://doi.org/10.1016/j.brs.2012.05.008 PDF Journal Link
Dmochowski, J. P., Bikson, M., & Parra, L. C. (2012). The point spread function of the human head and its implications for transcranial current stimulation. Physics in Medicine and Biology, 57(20), 6459-6477. https://doi.org/10.1088/0031-9155/57/20/6459 PDF
Kronberg, G., & Bikson, M. (2012). Electrode assembly design for transcranial direct current stimulation: A FEM modeling study. Paper presented at the Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS, 891-895. https://doi.org/10.1109/EMBC.2012.6346075 PDF
Truong, D. Q., Magerowski, G., Pascual-Leone, A., Alonso-Alonso, M., & Bikson, M. (2012). Finite element study of skin and fat delineation in an obese subject for transcranial direct current stimulation. Paper presented at the Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS, 6587-6590. https://doi.org/10.1109/EMBC.2012.6347504 PDF
Truong, D., Datta, A., Xu, J., Fregni, F., & Bikson, M. (2012). Prefrontal cortex transcranial direct current stimulation via a combined high definition and conventional electrode montage: A FEM modeling studying. Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference. 2012. 6608-11. https://doi.org/10.1109/EMBC.2012.6347509 PDF
Minhas, P., Bikson, M., Woods, A. J., Rosen, A. R., & Kessler, S. K. (2012). Transcranial direct current stimulation in pediatric brain: A computational modeling study. Paper presented at the Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS, 859-862. https://doi.org/10.1109/EMBC.2012.6346067 PDF Free PMIC
Arlotti, M., Rahman, A., Minhas, P., & Bikson, M. (2012). Axon terminal polarization induced by weak uniform DC electric fields: A modeling study. Paper presented at the Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS, 4575-4578. https://doi.org/10.1109/EMBC.2012.6346985 PDF
Dmochowski, J. P., Bikson, M., Datta, A., Richardson, J., Fridriksson, J., & Parra, L. C. (2012). On the role of electric field orientation in optimal design of transcranial current stimulation. Paper presented at the Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS, 6426-6429. https://doi.org/10.1109/EMBC.2012.6347465 PDF
Caparelli-Daquer, E. M., Zimmermann, T. J., Mooshagian, E., Parra, L. C., Rice, J. K., Datta, A., Bikson, M., & Wassermann, E. M. (2012). A pilot study on effects of 4×1 high-definition tDCS on motor cortex excitability. Paper presented at the Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS, 735-738. https://doi.org/10.1109/EMBC.2012.6346036 PDF
Bikson, M., Rahman, A., Datta, A., Fregni, F., & Merabet, L. (2012). High-resolution modeling assisted design of customized and individualized transcranial direct current stimulation protocols. Neuromodulation, 15(4), 306-315. https://doi.org/10.1111/j.1525-1403.2012.00481.x PDF
Elwassif, M. M., Datta, A., Rahman, A., & Bikson, M. (2012). Temperature control at DBS electrodes using a heat sink: Experimentally validated FEM model of DBS lead architecture. Journal of Neural Engineering, 9(4). https://doi.org/10.1088/1741-2560/9/4/046009 PDF
Borckardt, J. J., Bikson, M., Frohman, H., Reeves, S. T., Datta, A., Bansal, V., Madan, A., Barth, K., & George, M. S. (2012). A pilot study of the tolerability and effects of high-definition transcranial direct current stimulation (HD-tDCS) on pain perception. Journal of Pain, 13(2), 112-120. https://doi.org/10.1016/j.jpain.2011.07.001 PDF
Peterchev, A. V., Wagner, T. A., Miranda, P. C., Nitsche, M. A., Paulus, W., Lisanby, S. H., Pascual-Leone, A., & Bikson, M. (2012). Fundamentals of transcranial electric and magnetic stimulation dose: Definition, selection, and reporting practices. Brain Stimulation, 5(4), 435-453. https://doi.org/10.1016/j.brs.2011.10.001 PDF
Bikson, M., Reato, D., & Rahman, A. Cellular effects of electric and magnetic fields: insights animal models and in slice. Transcranial Brain Stimulation (Frontiers in Neuroscience) 2012 ed, Carolo Miniussi, Walter Paulus, Paolo M. Rossini. CRC Press. ISBN 978-1439875704, 55-92. PDF
Bikson, M., & Datta, A. (2012). Guidelines for precise and accurate computational models of tDCS. Brain Stimulation, 5(3), 430-431. https://doi.org/10.1016/j.brs.2011.06.001 PDF
Brunoni, A. R., Nitsche, M. A., Bolognini, N., Bikson, M., Wagner, T., Merabet, L., Edwards, D. J., Valero-Cabre, A., Rotenberg, A., Pascual-Leone, A., Ferrucci, R., Priori, A., Boggio, P. S., & Fregni, F. (2012). Clinical research with transcranial direct current stimulation (tDCS): Challenges and future directions. Brain Stimulation, 5(3), 175-195. https://doi.org/10.1016/j.brs.2011.03.002 PDF
2011
DaSilva, A. F., Volz, M. S., Bikson, M., & Fregni, F. (2011). Electrode positioning and montage in transcranial direct current stimulation. Journal of Visualized Experiments, (51). https://doi.org/10.3791/2744 PDF Video
Turkeltaub, P. E., Benson, J., Hamilton, R. H., Datta, A., Bikson, M., & Coslett, H. B. (2011). Left lateralizing transcranial direct current stimulation improves reading efficiency. Brain Stimulation, 5(3), 201-207. https://doi.org/10.1016/j.brs.2011.04.002 PDF
Dmochowski, J. P., Datta, A., Bikson, M., Su, Y., & Parra, L. C. (2011). Optimized multi-electrode stimulation increases focality and intensity at target. Journal of Neural Engineering, 8(4). https://doi.org/10.1088/1741-2560/8/4/046011 PDF
Datta, A., Baker, J. M., Bikson, M., & Fridriksson, J. (2011). Individualized model predicts brain current flow during transcranial direct-current stimulation treatment in responsive stroke patient. Brain Stimulation, 4(3), 169-174. https://doi.org/10.1016/j.brs.2010.11.001 PDF PubMed HTML
Halko, M. A., Datta, A., Plow, E. B., Scaturro, J., Bikson, M., & Merabet, L. B. (2011). Neuroplastic changes following rehabilitative training correlate with regional electrical field induced with tDCS. NeuroImage, 57(3), 885-891. https://doi.org/10.1016/j.neuroimage.2011.05.026 PDF
Mendonca, M. E., Santana, M. B., Baptista, A. F., Datta, A., Bikson, M., Fregni, F., & Araujo, C. P. (2011). Transcranial DC stimulation in fibromyalgia: Optimized cortical target supported by high-resolution computational models. Journal of Pain, 12(5), 610-617. https://doi.org/10.1016/j.jpain.2010.12.015 PDF
Minhas, P., Datta, A., & Bikson, M. (2011). Cutaneous perception during tDCS: Role of electrode shape and sponge salinity. Clinical Neurophysiology, 122(4), 637-638. https://doi.org/10.1016/j.clinph.2010.09.023 PDF
Bikson, M., Datta, A., Elwassif, M., Bansal, V., & Peterchev, A. V. (2011). Introduction to electrotherapy technology. Pain. brain stimulation in the treatment of pain, 1-13. PDF
Dmochowski, J. P., Bikson, M., Datta, A., Su, Y., & Parra, L. C. (2011). A multiple electrode scheme for optimal non-invasive electrical stimulation. Paper presented at the 2011 5th International IEEE/EMBS Conference on Neural Engineering, NER 2011, 29-35. https://doi.org/10.1109/NER.2011.5910482 PDF
2010
Reato, D., Rahman, A., Bikson, M., & Parra, L. C. (2010). Low-intensity electrical stimulation affects network dynamics by modulating population rate and spike timing. Journal of Neuroscience, 30(45), 15067-15079. https://doi.org/10.1523/JNEUROSCI.2059-10.2010 PDF
Servais, E. L., Rizk, N. P., Oliveira, L., Rusch, V. W., Bikson, M., & Adusumilli, P. S. (2010). Real-time intraoperative detection of tissue hypoxia in gastrointestinal surgery by wireless pulse oximetry. Surgical Endoscopy, 25(5), 1383-1389. https://doi.org/10.1007/s00464-010-1372-8 PDF
Bikson, M., Datta, A., Rahman, A., & Scaturro, J. (2010). Electrode montages for tDCS and weak transcranial electrical stimulation: Role of " return" electrode's position and size. Clinical Neurophysiology, 121(12), 1976-1978. https://doi.org/10.1016/j.clinph.2010.05.020 PDF
Minhas, P., Bansal, V., Patel, J., Ho, J. S., Diaz, J., Datta, A., & Bikson, M. (2010). Electrodes for high-definition transcutaneous DC stimulation for applications in drug delivery and electrotherapy, including tDCS. Journal of Neuroscience Methods, 190(2), 188-197. https://doi.org/10.1016/j.jneumeth.2010.05.007 PDF
Datta, A., Bikson, M., & Fregni, F. (2010). Transcranial direct current stimulation in patients with skull defects and skull plates: High-resolution computational FEM study of factors altering cortical current flow. NeuroImage, 52(4), 1268-1278. https://doi.org/10.1016/j.neuroimage.2010.04.252 PDF
Sunderam, S., Gluckman, B., Reato, D., & Bikson, M. (2010). Toward rational design of electrical stimulation strategies for epilepsy control. Epilepsy and Behavior, 17(1), 6-22. https://doi.org/10.1016/j.yebeh.2009.10.017 PDF
Lopez-Quintero, S. V., Datta, A., Amaya, R., Elwassif, M., Bikson, M., & Tarbell, J. M. (2010). DBS-relevant electric fields increase hydraulic conductivity of in vitro endothelial monolayers. Journal of Neural Engineering, 7(1). https://doi.org/10.1088/1741-2560/7/1/016005 PDF
2009
Radman, T., Ramos, R. L., Brumberg, J. C., & Bikson, M. (2009). Role of cortical cell type and morphology in subthreshold and suprathreshold uniform electric field stimulation in vitro. Brain Stimulation, 2(4), 215-228.e3. https://doi.org/10.1016/j.brs.2009.03.007 PDF
Datta, A., Bansal, V., Diaz, J., Patel, J., Reato, D., & Bikson, M. (2009). Gyri-precise head model of transcranial direct current stimulation: Improved spatial focality using a ring electrode versus conventional rectangular pad. Brain Stimulation, 2(4), 201-207.e1. https://doi.org/10.1016/j.brs.2009.03.005 PDF
Bikson, M., Datta, A., & Elwassif, M. (2009). Establishing safety limits for transcranial direct current stimulation. Clinical Neurophysiology, 120(6), 1033-1034. https://doi.org/10.1016/j.clinph.2009.03.018 PDF
Datta, A., Elwassif, M., & Bikson, M. (2009). Bio-heat transfer model of transcranial DC stimulation: Comparison of conventional pad versus ring electrode. Paper presented at the Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009, 670-673. https://doi.org/10.1109/IEMBS.2009.5333673 PDF
2008
Bikson, M., Bulow, P., Stiller, J. W., Datta, A., Battaglia, F., Karnup, S. V., & Postolache, T. T. (2008). Transcranial direct current stimulation for major depression: A general system for quantifying transcranial electrotherapy dosage. Current Treatment Options in Neurology, 10(5), 377-385. https://doi.org/10.1007/s11940-008-0040-y PDF
Datta, A., Elwassif, M., Battaglia, F., & Bikson, M. (2008). Transcranial current stimulation focality using disc and ring electrode configurations: FEM analysis. Journal of Neural Engineering, 5(2), 163-174. https://doi.org/10.1088/1741-2560/5/2/007 PDF
An, J. H., Su, Y., Radman, T., & Bikson, M. (2008). Effects of glucose and glutamine concentration in the formulation of the artificial cerebrospinal fluid (ACSF). Brain Research, 1218, 77-86. https://doi.org/10.1016/j.brainres.2008.04.007 PDF
Su, Y., Radman, T., Vaynshteyn, J., Parra, L. C., & Bikson, M. (2008). Effects of high-frequency stimulation on epileptiform activity in vitro: ON/OFF control paradigm. Epilepsia, 49(9), 1586-1593. https://doi.org/10.1111/j.1528-1167.2008.01592.x PDF
2007
Radman, T., Su, Y., Je, H. A., Parra, L. C., & Bikson, M. (2007). Spike timing amplifies the effect of electric fields on neurons: Implications for endogenous field effects. Journal of Neuroscience, 27(11), 3030-3036. https://doi.org/10.1523/JNEUROSCI.0095-07.2007 PDF
Fox, J. E., Bikson, M., & Jefferys, J. G. R. (2007). The effect of neuronal population size on the development of epileptiform discharges in the low calcium model of epilepsy. Neuroscience Letters, 411(2), 158-161. https://doi.org/10.1016/j.neulet.2006.10.021 PDF
1999-2006
Elwassif, M. M., Kong, Q., Vazquez, M., & Bikson, M. (2006). Bio-heat transfer model of deep brain stimulation-induced temperature changes. Journal of Neural Engineering, 3(4). https://doi.org/10.1088/1741-2560/3/4/008 PDF
Merrill, D. R., Bikson, M., & Jefferys, J. G. R. (2005). Electrical stimulation of excitable tissue: Design of efficacious and safe protocols. Journal of Neuroscience Methods, 141(2), 171-198. https://doi.org/10.1016/j.jneumeth.2004.10.020 PDF
Fox, J. E., Bikson, M., & Jefferys, J. G. R. (2004). Tissue resistance changes and the profile of synchronized neuronal activity during ictal events in the low-calcium model of epilepsy. Journal of Neurophysiology, 92(1), 181-188. https://doi.org/10.1152/jn.00123.2004 PDF
Bikson, M., Inoue, M., Akiyama, H., Deans, J. K., Fox, J. E., Miyakawa, H., & Jefferys, J. G. R. (2004). Effects of uniform extracellular DC electric fields on excitability in rat hippocampal slices in vitro. Journal of Physiology, 557(1), 175-190. https://doi.org/10.1113/jphysiol.2003.055772 PDF
Durand, D. M., & Bikson, M. (2003). Control of neuronal activity by electric fields: in-vitro models of epilepsy. In H. O. Luders, Deep Brain Stimulation and Epilepsy. Boca Raton, FL: CRC Press.
Bikson, M., Hahn, P. J., Fox, J. E., & Jefferys, J. G. R. (2003). Depolarization block of neurons during maintenance of electrographic seizures. Journal of Neurophysiology, 90(4), 2402-2408. https://doi.org/10.1152/jn.00467.2003 PDF
Jefferys, J. G., Deans, J., Bikson, M., & Fox, J. (2003). Effects of weak electric fields on the activity of neurons and neuronal networks. Radiation protection dosimetry, 106(4), 321–323. https://doi.org/10.1093/oxfordjournals.rpd.a006367 PDF
Shuai, J., Bikson, M., Hahn, P. J., Lian, J., & Durand, D. M. (2003). Ionic mechanisms underlying spontaneous CA1 neuronal firing in CA2+-free solution. Biophysical Journal, 84(3), 2099-2111. https://doi.org/10.1016/S0006-3495(03)75017-6 PDF
Lian, J., Bikson, M., Sciortino, C., Stacey, W. C., & Durand, D. M. (2003). Local suppression of epileptiform activity by electrical stimulation in rat hippocampus in vitro. Journal of Physiology, 547(2), 427-434. https://doi.org/10.1113/jphysiol.2002.033209 PDF
Bikson, M., Fox, J. E., & Jefferys, J. G. (2003). Neuronal aggregate formation underlies spatiotemporal dynamics of nonsynaptic seizure initiation. Journal of neurophysiology, 89(4), 2330–2333. https://doi.org/10.1152/jn.00764.2002 PDF
Bikson, M., Id Bihi, R., Vreugdenhil, M., Köhling, R., Fox, J. E., & Jefferys, J. G. R. (2002). Quinine suppresses extracellular potassium transients and ictal epileptiform activity without decreasing neuronal excitability in vitro. Neuroscience, 115(1), 251-261. https://doi.org/10.1016/S0306-4522(02)00320-2 PDF
Lian, J., Bikson, M., Shuai, J., & Durand, D. M. (2001). Propagation of non-synaptic epileptiform activity across a lesion in rat hippocampal slices. Journal of Physiology, 537(1), 191-199. https://doi.org/10.1111/j.1469-7793.2001.0191k.x PDF
Bikson, M., Baraban, S. C., & Durand, D. M. (2001). Conditions sufficient for non-synaptic epileptogenesis in the CA1 region of rat hippocampal slices. Journal of Neurophysiology, 87(1), 62-71. https://doi.org/10.1152/jn.00196.2001 PDF
Bikson, M., Lian, J., Hahn, P. J., Stacey, W. C., Sciortino, C., & Durand, D. M. (2001). Suppression of epileptiform activity by high frequency sinusoidal fields in rat hippocampal slices. Journal of Physiology, 531(1), 181-191. https://doi.org/10.1111/j.1469-7793.2001.0181j.x PDF
Durand, D. M., & Bikson, M. (2001). Suppression and control of epileptiform activity by electrical stimulation: A review. Proceedings of the IEEE, 89(7), 1065-1082. https://doi.org/10.1109/5.939821 PDF
Ghai, R. S., Bikson, M., & Durand, D. M. (2000). Effects of applied electric fields on low-calcium epileptiform activity in the CA1 region of rat hippocampal slices. Journal of Neurophysiology, 84(1), 274-280. https://doi.org/10.1152/jn.2000.84.1.274 PDF
Bikson, M., Ghai, R. S., Baraban, S. C., & Durand, D. M. (1999). Modulation of burst frequency, duration, and amplitude in the zero- Ca2+ model of epileptiform activity. Journal of Neurophysiology, 82(5), 2262-2270. https://doi.org/10.1152/jn.1999.82.5.2262 PDF
Media / Selected Professional Activities
Also visit CCNY Neural Engineering Group NEWS
2023 News coverage of NIH RECOVER tDCS trial. Reuters, Washington Post, NIH, Yahoo Finance, Biospace, Medical Device Network
2023 New coverages for JAMA open network trial of HD-tDCS for acute stroke in Medical News Today, Medscape, 2-Minute Medicine, Medical Xpress, Medical Daily
2022 Newsy “Breakthrough device could easy deep depression” watch
2022 MIT Tech Review link (article quotes Marom Bikson and features HD-tACS to improve memory in older adults. HD-tACS was co-invented by Dr. Bikson. See additional news on the breakthrough.)
2022 IEEE Spectrum link
2021 Neural Implant Podcast listen
2021 CCNY link
2019 NPR link
2019 The Economist and Slate link
2017 IBM thinkLeaders link
2017 HBO – VICE news watch
2016 TEDx Bushwick watch
2016 Al Jazeera America watch
2016 SmartHealth Personal Feature link
2015 New Statesman link
2015 Motherboard link
2015 La Vangaurdia (pesonal feature on paper back page) link
2015 PBS newhour watch
2015 Member Boston Scientific advisory board
2015 Chair, NYC Neuromodulation Jan 9, 2015 link
2014 MIT Tech Review Nov 10, 2014 link
2014 Scientific American Mind: Your Electric Pharmay Nov 2014 link
2014 NPR “Hacking The Brain With Electricity: Don’t Try This At Home” link May 19, 2014
2014 FrenchTV “Electrodes for a Better Brain” video in french May 20, 2014
2014 WIRED magazine “The Unfinished Science Behind the New Wave of Electrical Brain Stimulation” link May 5, 2014
2014 IEEE-Spectrum “The Latest DIY Craze: Brain Hacking” link
2014 KQED (NPR) “Is Brain Stimulation a Medicine of the Future” link
2013 Chair: NYCneuromodulation conference Program link
2013 DIYtDCS PodCast audio interview link
Runner’s World “Zap Your Brain to Run Faster” link Feb 27, 2013
2012 “Electrical brain stimulation gains ground” San Fransico Chronicle; Oct 30, 2012 link
2012 “tDCS Course” at Harvard Medical School Lecture on “tDCS Dose and Mechanism.” Watch the talk- Low Res Version Only or on YouTube