Neural Engineering Group Lab Meeting

Wen Aug 31st 1-2 PM. BME Conference Room

Topic: Ephaptic coupling of cortical neurons.

Nat Neurosci. 2011 Feb;14(2):217-23. by Anastassiou CA, Perin R, Markram H, Koch C.

Abstract: The electrochemical processes that underlie neural function manifest themselves in ceaseless spatiotemporal field fluctuations. However, extracellular fields feed back onto the electric potential across the neuronal membrane via ephaptic coupling, independent of synapses. The extent to which such ephaptic coupling alters the functioning of neurons under physiological conditions remains unclear. To address this question, we stimulated and recorded from rat cortical pyramidal neurons in slices with a 12-electrode setup. We found that extracellular fields induced ephaptically mediated changes in the somatic membrane potential that were less than 0.5 mV under subthreshold conditions. Despite their small size, these fields could strongly entrain action potentials, particularly for slow (<8 Hz) fluctuations of the extracellular field. Finally, we simultaneously measured from up to four patched neurons located proximally to each other. Our findings indicate that endogenous brain activity can causally affect neural function through field effects under physiological conditions.

pubmed   paper

Our High-Definition tDCS featured in FUTURE TECHNOLOGY TRENDS

Blog Article Link

“This new tDCS device has been developed by scientists at the [City Collegeof New York] Neural Engineering group.  Instead of utilizing two electrodes like you would find with conventional tDCS, this is an entire cap that has many of them and is similar to an EEG.  More regions of the brain can thus be adjusted than would normally be possible.  It is possible to hook this device up to a computer and allow it to deliver controlled stimulaiton to almost any region located close to a person’s skull.”

NYC Tech Connect (an initiative of The New York City Investment Fund) invites you to the kickoff event of our new, monthly Speaker’s Series — Riverside Chats.  This series is designed for graduate students and post docs in the biosciences at all New York universities.    Each event will focus on some aspect of entrepreneurship, technology commercialization and funding sources.   Come to learn and network with NYC’s best and brightest entrepreneurial minds in the biosciences.

Host and partner: MSKCC’s Office of Technology Development (OTD).  All events will take place at the Rockefeller Board Room at 430 E. 67th St. (between York and 1st).

When:    Tuesday, August 9, 2011,  6-6:30 p.m. – program 6:30-7:30 p.m. – networking / cocktail hour

Topic:      The BioAccelerate NYC Prizea $250,000 funding opportunity!

Speakers:    Jahan Ali, Senior Vice President, New York City Investment Fund and Dr. Sheila Nirenberg, Weill                           Cornell Medical College – 2011 Winner

RSVP required: events@nyctechconnect.com

(Save the Monthly Dates for upcoming events: September 13 / October 10 / November 8 / December 13)

Two CCNY Neural Engineering modeling papers published in leading journals- Innovation in tDCS optimization and tDCS in stroke.

Datta A, Baker J, Bikson M, Fridriksson F. Individualized model predicts brain current flow during transcranial direct-current stimulation treatment in responsive stroke patient. Brain Stimulation2011; 4: 169-74 read it

Dmochowski JP, Datta A, Bikson M, Su Y, Parra LC. Optimized multi-electrode stimulation increases focality and intensity at target. Journal of Neural Engineering . 2011; 8(4) read it

 

“thinking BIG” – Electrical brain stimulation technology features in CUNY Matters

HTML article here  July 11, 2011 | CUNY Matters, The University

“University researchers are now developing marketable products to help solve medical, energy and other global challenges. These profitable ideas will also benefit CUNY and the local economy.

What if. For science and technology researchers, these are the words that can start an idea on the road to invention — the connective tissue between something known and something imagined. In recent years, a particular brand of what-if has been percolating in labs around the University: the kind that can lead to something the world can really use…

What if electrical brain stimulation, a technique that has shown promise as a treatment for diseases like Parkinson’s, could be accomplished by simply placing electrodes on the scalp — rather than requiring a surgeon to drill a hole through the skull, as the technology now requires”

Marom_Bikson_ThinkBig_CUNYmatter

Marom_Bikson_CUNYmatters_Brainstim

“thinking BIG” – Electrical brain stimulation technology features in CUNY Matters

HTML article here  July 11, 2011 | CUNY Matters, The University

“University researchers are now developing marketable products to help solve medical, energy and other global challenges. These profitable ideas will also benefit CUNY and the local economy.

What if. For science and technology researchers, these are the words that can start an idea on the road to invention — the connective tissue between something known and something imagined. In recent years, a particular brand of what-if has been percolating in labs around the University: the kind that can lead to something the world can really use…

What if electrical brain stimulation, a technique that has shown promise as a treatment for diseases like Parkinson’s, could be accomplished by simply placing electrodes on the scalp — rather than requiring a surgeon to drill a hole through the skull, as the technology now requires”

Marom_Bikson_ThinkBig_CUNYmatter

Marom_Bikson_CUNYmatters_Brainstim

CUNY Entrepreneurship Workshop

THE CUNY CENTER FOR ADVANCED TECHNOLOGY AND THE FIELD CENTER FOR ENTREPRENEURSHIP AT BARUCH COLLEGE – FALL 2011 FACULTY ENTREPRENEURSHIP WORKSHOP

The innovation economy of the 21st century will place a premium on rapid migration of research results from the university laboratory to the marketplace. For the past several years, CUNY’s Center for Advanced Technology (CAT) has worked with science and engineering faculty and research associates to help them understand the decisions they must make, and their consequences, as they seek commercial opportunities for their research.

More details and Register

Prof. Marom Bikson will speak on panel on entrepreneurship in New York City. (7:00-8:00PM on September 14th, Baruch College)